Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DC74_4142Branched-chain alpha-keto acid dehydrogenase subunit E2. (488 aa)    
Predicted Functional Partners:
DC74_4143
E1-beta branched-chain alpha-keto-acid dehydrogenase system.
 
 0.999
pdhA_1
Putative branched-chain alpha keto acid dehydrogenase E1 alpha subunit.
 
 0.998
DC74_4157
Putative branched-chain alpha keto acid dehydrogenase E1 beta subunit.
 
 0.997
DC74_4158
3-methyl-2-oxobutanoate dehydrogenase (lipoamide) E1-alpha chain.
 
 0.995
DC74_2672
Dihydrolipoamide dehydrogenase.
 0.994
pdhD
Dihydrolipoamide dehydrogenase.
 0.989
DC74_1036
Citrate synthase; Belongs to the citrate synthase family.
  
 0.962
pta
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
  
 
 0.947
DC74_2673
Dihydrolipoamide S-succinyltransferase.
 
  
 
0.940
DC74_5432
Alpha-ketoglutarate decarboxylase.
 
0.935
Your Current Organism:
Streptomyces albulus
NCBI taxonomy Id: 68570
Other names: ATCC 12757, BCRC 11819, CBS 711.72, CCRC 11819, CCRC:11819, DSM 40492, IFO 13410, ISP 5492, JCM 4718, KCTC 9668, NBRC 13410, NRRL B-5386, NRRL-ISP 5492, S. albulus, strain IMC S-0802
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