| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DC74_226 | DC74_2307 | DC74_226 | DC74_2307 | Class V aminotransferase. | 3-phosphoserine phosphatase. | 0.915 |
| DC74_226 | DC74_3524 | DC74_226 | DC74_3524 | Class V aminotransferase. | Cystathionine beta-synthase. | 0.913 |
| DC74_226 | DC74_4255 | DC74_226 | DC74_4255 | Class V aminotransferase. | Hypothetical protein. | 0.915 |
| DC74_226 | DC74_7699 | DC74_226 | DC74_7699 | Class V aminotransferase. | Cystathionine beta-synthase. | 0.913 |
| DC74_226 | glyA | DC74_226 | DC74_5030 | Class V aminotransferase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.920 |
| DC74_226 | glyA-2 | DC74_226 | DC74_5595 | Class V aminotransferase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.920 |
| DC74_226 | glyA_2 | DC74_226 | DC74_5476 | Class V aminotransferase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.920 |
| DC74_226 | sdaA | DC74_226 | DC74_5594 | Class V aminotransferase. | L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.910 |
| DC74_226 | trpB_2 | DC74_226 | DC74_2513 | Class V aminotransferase. | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.912 |
| DC74_2307 | DC74_226 | DC74_2307 | DC74_226 | 3-phosphoserine phosphatase. | Class V aminotransferase. | 0.915 |
| DC74_2307 | DC74_3524 | DC74_2307 | DC74_3524 | 3-phosphoserine phosphatase. | Cystathionine beta-synthase. | 0.933 |
| DC74_2307 | DC74_4255 | DC74_2307 | DC74_4255 | 3-phosphoserine phosphatase. | Hypothetical protein. | 0.906 |
| DC74_2307 | DC74_7699 | DC74_2307 | DC74_7699 | 3-phosphoserine phosphatase. | Cystathionine beta-synthase. | 0.933 |
| DC74_2307 | glyA | DC74_2307 | DC74_5030 | 3-phosphoserine phosphatase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.939 |
| DC74_2307 | glyA-2 | DC74_2307 | DC74_5595 | 3-phosphoserine phosphatase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.939 |
| DC74_2307 | glyA_2 | DC74_2307 | DC74_5476 | 3-phosphoserine phosphatase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.939 |
| DC74_2307 | sdaA | DC74_2307 | DC74_5594 | 3-phosphoserine phosphatase. | L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.949 |
| DC74_2307 | serC | DC74_2307 | DC74_4843 | 3-phosphoserine phosphatase. | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.976 |
| DC74_2307 | trpB_2 | DC74_2307 | DC74_2513 | 3-phosphoserine phosphatase. | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.926 |
| DC74_3524 | DC74_226 | DC74_3524 | DC74_226 | Cystathionine beta-synthase. | Class V aminotransferase. | 0.913 |