DC74_4489 protein (Streptomyces albulus) - STRING interaction network

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Score

DC74_4489

Putative serine protease. (399 aa)

Predicted Functional Partners:

DC74_4488

0.890

arc

0.817

nth

0.808

DC74_2643

0.703

DC74_5122

0.700

DC74_5576

0.688

DC74_5575

0.680

glpK2

0.667

DC74_3663

0.647

DC74_4486

0.630

Your Current Organism:

Streptomyces albulus

NCBI taxonomy Id: 68570
Other names: ATCC 12757, BCRC 11819, CBS 711.72, CCRC 11819, CCRC:11819, DSM 40492, IFO 13410, ISP 5492, JCM 4718, KCTC 9668, NBRC 13410, NRRL B-5386, NRRL-ISP 5492, S. albulus, strain IMC S-0802

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DC74_2643	DC74_4489	DC74_2643	DC74_4489	Lipoprotein.	Putative serine protease.	0.703
DC74_3663	DC74_4489	DC74_3663	DC74_4489	Lipoprotein.	Putative serine protease.	0.647
DC74_4486	DC74_4488	DC74_4486	DC74_4488	Crp/Fnr family transcriptional regulator.	Hypothetical protein.	0.658
DC74_4486	DC74_4489	DC74_4486	DC74_4489	Crp/Fnr family transcriptional regulator.	Putative serine protease.	0.630
DC74_4486	arc	DC74_4486	DC74_2117	Crp/Fnr family transcriptional regulator.	Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.	0.404
DC74_4486	nth	DC74_4486	DC74_4487	Crp/Fnr family transcriptional regulator.	Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.	0.737
DC74_4488	DC74_4486	DC74_4488	DC74_4486	Hypothetical protein.	Crp/Fnr family transcriptional regulator.	0.658
DC74_4488	DC74_4489	DC74_4488	DC74_4489	Hypothetical protein.	Putative serine protease.	0.890
DC74_4488	nth	DC74_4488	DC74_4487	Hypothetical protein.	Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.	0.809
DC74_4489	DC74_2643	DC74_4489	DC74_2643	Putative serine protease.	Lipoprotein.	0.703
DC74_4489	DC74_3663	DC74_4489	DC74_3663	Putative serine protease.	Lipoprotein.	0.647
DC74_4489	DC74_4486	DC74_4489	DC74_4486	Putative serine protease.	Crp/Fnr family transcriptional regulator.	0.630
DC74_4489	DC74_4488	DC74_4489	DC74_4488	Putative serine protease.	Hypothetical protein.	0.890
DC74_4489	DC74_5122	DC74_4489	DC74_5122	Putative serine protease.	Putative lipoprotein.	0.700
DC74_4489	DC74_5575	DC74_4489	DC74_5575	Putative serine protease.	Lipoprotein.	0.680
DC74_4489	DC74_5576	DC74_4489	DC74_5576	Putative serine protease.	Putative lipoprotein.	0.688
DC74_4489	arc	DC74_4489	DC74_2117	Putative serine protease.	Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.	0.817
DC74_4489	glpK2	DC74_4489	DC74_2130	Putative serine protease.	Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.	0.667
DC74_4489	nth	DC74_4489	DC74_4487	Putative serine protease.	Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.	0.808
DC74_5122	DC74_4489	DC74_5122	DC74_4489	Putative lipoprotein.	Putative serine protease.	0.700

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