Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
DC74_4545Activator of HSP90 ATPase 1 family protein. (160 aa)    
Predicted Functional Partners:
DC74_4544
ArsR family transcriptional regulator.
 
  
 0.940
DC74_4546
Putative regulator.
       0.758
rpsR2
30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.
       0.749
DC74_4542
Hypothetical protein.
       0.696
rpmG1
50S ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family.
       0.652
DC74_7725
Putative transcriptional regulator.
 
    0.538
rpmB2
50S ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family.
       0.473
rpmE2-2
50S ribosomal protein L31 type B.
       0.471
rpsN-2
30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.
       0.454
DC74_6864
ArsR family transcriptional regulator.
 
    0.433
Your Current Organism:
Streptomyces albulus
NCBI taxonomy Id: 68570
Other names: ATCC 12757, BCRC 11819, CBS 711.72, CCRC 11819, CCRC:11819, DSM 40492, IFO 13410, ISP 5492, JCM 4718, KCTC 9668, NBRC 13410, NRRL B-5386, NRRL-ISP 5492, S. albulus, strain IMC S-0802
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