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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
panCPantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (400 aa)    
Predicted Functional Partners:
panD
Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
 
 
 0.999
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
  
 0.997
coaX
Hypothetical protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
  
 
 0.996
DC74_4586
Hypothetical protein.
   
 0.987
DC74_4589
Nicotinate-nucleotide pyrophosphorylase.
 
   
 0.953
DC74_4588
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
 
   
 0.942
coaA
Pantothenate kinase.
     
 0.936
DC74_1434
Putative glutamate decarboxylase; Belongs to the group II decarboxylase family.
  
 
 0.930
DC74_4552
Glutamate decarboxylase; Belongs to the group II decarboxylase family.
  
 
 0.930
DC74_4030
Hypothetical protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.914
Your Current Organism:
Streptomyces albulus
NCBI taxonomy Id: 68570
Other names: ATCC 12757, BCRC 11819, CBS 711.72, CCRC 11819, CCRC:11819, DSM 40492, IFO 13410, ISP 5492, JCM 4718, KCTC 9668, NBRC 13410, NRRL B-5386, NRRL-ISP 5492, S. albulus, strain IMC S-0802
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