STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DC74_4813-carboxy-cis,cis-muconate cycloisomerase. (469 aa)    
Predicted Functional Partners:
DC74_482
Protocatechuate 3,4-dioxygenase alpha subunit.
 
 
 0.997
DC74_483
Protocatechuate 3,4-dioxygenase beta subunit.
 
 
 0.997
DC74_6310
Protocatechuate 3,4-dioxygenase alpha subunit.
 
 
 0.991
DC74_6309
Protocatechuate 3,4-dioxygenase subunit beta.
 
 
 0.989
DC74_6435
3-oxoadipate enol-lactone hydrolase.
 
 
 0.980
DC74_6311
3-oxoadipate enol-lactone hydrolase.
 
 
 0.974
purE
Phosphoribosylaminoimidazole carboxylase catalytic subunit PurE; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
  
 
 0.958
purK
Phosphoribosylaminoimidazole carboxylase ATPase PurK; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
  
 
 0.958
DC74_880
Carboxymuconolactone decarboxylase family protein.
 
 
 0.958
purC
Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family.
  
 
 0.957
Your Current Organism:
Streptomyces albulus
NCBI taxonomy Id: 68570
Other names: ATCC 12757, BCRC 11819, CBS 711.72, CCRC 11819, CCRC:11819, DSM 40492, IFO 13410, ISP 5492, JCM 4718, KCTC 9668, NBRC 13410, NRRL B-5386, NRRL-ISP 5492, S. albulus, strain IMC S-0802
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