Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EIC27956.1PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; LysR substrate binding domain; Belongs to the LysR transcriptional regulatory family. (296 aa)    
Predicted Functional Partners:
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.591
EIC31295.1
PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; LysR substrate binding domain; Belongs to the LysR transcriptional regulatory family.
  
     0.531
EIC27955.1
Sulfate permease-like transporter, MFS superfamily; PFAM: Sulfate transporter family.
       0.513
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.499
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
   0.496
EIC29200.1
PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
     
 0.469
rpoC
DNA-directed RNA polymerase, beta'' subunit, predominant form; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.452
EIC29720.1
PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; LysR substrate binding domain; Belongs to the LysR transcriptional regulatory family.
  
     0.438
EIC28322.1
PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; LysR substrate binding domain; Belongs to the LysR transcriptional regulatory family.
  
     0.428
EIC30205.1
PFAM: Adenylate cyclase, class-I.
  
   
 0.410
Your Current Organism:
Methylomicrobium album
NCBI taxonomy Id: 686340
Other names: M. album BG8, Methylomicrobium album BG8, Methylomicrobium album str. BG8, Methylomicrobium album strain BG8
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