Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EIC27977.1Fe2+/Zn2+ uptake regulation protein; PFAM: Ferric uptake regulator family; Belongs to the Fur family. (156 aa)    
Predicted Functional Partners:
EIC29200.1
PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
    
 0.911
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.713
EIC27976.1
Outer membrane receptor for ferrienterochelin and colicin; PFAM: TonB-dependent Receptor Plug Domain; TonB dependent receptor.
 
   
 0.688
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.558
rpoC
DNA-directed RNA polymerase, beta'' subunit, predominant form; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.527
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
   0.516
EIC27972.1
PFAM: Protein of unknown function (DUF1826).
       0.492
folE2
Hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate.
  
    0.485
EIC27975.1
Putative GTPase, G3E family; PFAM: CobW/HypB/UreG, nucleotide-binding domain; Cobalamin synthesis protein cobW C-terminal domain.
     
 0.482
EIC28149.1
Peroxiredoxin; PFAM: C-terminal domain of 1-Cys peroxiredoxin; AhpC/TSA family.
  
  
 0.467
Your Current Organism:
Methylomicrobium album
NCBI taxonomy Id: 686340
Other names: M. album BG8, Methylomicrobium album BG8, Methylomicrobium album str. BG8, Methylomicrobium album strain BG8
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