Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ureBPFAM: Urease beta subunit; TIGRFAM: urease, beta subunit; Belongs to the urease beta subunit family. (110 aa)    
Predicted Functional Partners:
ureA
PFAM: Urease, gamma subunit; TIGRFAM: urease, gamma subunit; Belongs to the urease gamma subunit family.
 0.999
ureC
PFAM: Urease alpha-subunit, N-terminal domain; Amidohydrolase family; TIGRFAM: urease, alpha subunit.
 0.999
ureF
Urease accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
 
 0.991
ureD
Urease accessory protein UreH; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
 
 0.990
ureE
Urease accessory protein UreE; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family.
 
   
 0.943
ureG
Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
 
  
 0.914
EIC28434.1
Urea carboxylase; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; Biotin carboxylase C-terminal domain; Allophanate hydrolase subunit 2; Carbamoyl-phosphate synthase L chain, N-terminal domain; Allophanate hydrolase subunit 1; Biotin-requiring enzyme; TIGRFAM: urea carboxylase; biotin-dependent carboxylase uncharacterized domain.
     
 0.881
EIC31096.1
2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase; PFAM: Fumarylacetoacetate (FAA) hydrolase family.
     
  0.676
EIC28394.1
Hydrogenase/urease accessory protein; PFAM: HupE / UreJ protein.
  
  
 0.675
EIC28435.1
PFAM: Amidase; TIGRFAM: allophanate hydrolase.
     
  0.642
Your Current Organism:
Methylomicrobium album
NCBI taxonomy Id: 686340
Other names: M. album BG8, Methylomicrobium album BG8, Methylomicrobium album str. BG8, Methylomicrobium album strain BG8
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