Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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Score
ureFUrease accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. (225 aa)    
Predicted Functional Partners:
ureC
PFAM: Urease alpha-subunit, N-terminal domain; Amidohydrolase family; TIGRFAM: urease, alpha subunit.
 
 
 0.994
ureD
Urease accessory protein UreH; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
 
 0.992
ureB
PFAM: Urease beta subunit; TIGRFAM: urease, beta subunit; Belongs to the urease beta subunit family.
 
 
 0.991
ureE
Urease accessory protein UreE; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family.
 
  
 0.980
ureA
PFAM: Urease, gamma subunit; TIGRFAM: urease, gamma subunit; Belongs to the urease gamma subunit family.
 
 
 0.973
ureG
Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
 
 
 0.966
EIC28392.1
Urea ABC transporter, ATP-binding protein UrtD; PFAM: ABC transporter; Branched-chain amino acid ATP-binding cassette transporter; TIGRFAM: urea ABC transporter, ATP-binding protein UrtD.
 
   
 0.814
EIC28968.1
Hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB.
  
 
 0.801
EIC28391.1
Urea ABC transporter, permease protein UrtC; PFAM: Branched-chain amino acid transport system / permease component; TIGRFAM: urea ABC transporter, permease protein UrtC; Belongs to the binding-protein-dependent transport system permease family.
 
   
 0.788
EIC28390.1
Urea ABC transporter, permease protein UrtB; PFAM: Branched-chain amino acid transport system / permease component; TIGRFAM: urea ABC transporter, permease protein UrtB; Belongs to the binding-protein-dependent transport system permease family.
 
   
 0.780
Your Current Organism:
Methylomicrobium album
NCBI taxonomy Id: 686340
Other names: M. album BG8, Methylomicrobium album BG8, Methylomicrobium album str. BG8, Methylomicrobium album strain BG8
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