| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EIC28637.1 | EIC28638.1 | Metal_0807 | Metal_0808 | PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region. | PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal; TIGRFAM: phosphate regulon transcriptional regulatory protein PhoB. | 0.497 |
| EIC28637.1 | EIC28639.1 | Metal_0807 | Metal_0809 | PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region. | Phosphate regulon sensor kinase PhoR; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; Domain of unknown function (DUF3329); TIGRFAM: phosphate regulon sensor kinase PhoR. | 0.482 |
| EIC28637.1 | EIC28814.1 | Metal_0807 | Metal_0995 | PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region. | Exodeoxyribonuclease III; PFAM: Endonuclease/Exonuclease/phosphatase family; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III (xth). | 0.776 |
| EIC28637.1 | EIC30555.1 | Metal_0807 | Metal_2868 | PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region. | N-methylhydantoinase B/acetone carboxylase, alpha subunit; PFAM: Hydantoinase/oxoprolinase; Hydantoinase B/oxoprolinase; Hydantoinase/oxoprolinase N-terminal region. | 0.710 |
| EIC28637.1 | EIC30878.1 | Metal_0807 | Metal_3207 | PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region. | PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; TIGRFAM: S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | 0.535 |
| EIC28637.1 | birA | Metal_0807 | Metal_0899 | PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region. | birA, biotin-(acetyl-CoA-carboxylase) ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.887 |
| EIC28637.1 | hisE | Metal_0807 | Metal_1327 | PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region. | PFAM: Phosphoribosyl-ATP pyrophosphohydrolase; TIGRFAM: phosphoribosyl-ATP pyrophosphohydrolase. | 0.557 |
| EIC28637.1 | mscL | Metal_0807 | Metal_0806 | PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region. | Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. | 0.552 |
| EIC28637.1 | ribB | Metal_0807 | Metal_0264 | PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.644 |
| EIC28637.1 | ribBA | Metal_0807 | Metal_3906 | PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region. | GTP cyclohydrolase II/3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.644 |
| EIC28638.1 | EIC28637.1 | Metal_0808 | Metal_0807 | PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal; TIGRFAM: phosphate regulon transcriptional regulatory protein PhoB. | PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region. | 0.497 |
| EIC28638.1 | EIC28639.1 | Metal_0808 | Metal_0809 | PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal; TIGRFAM: phosphate regulon transcriptional regulatory protein PhoB. | Phosphate regulon sensor kinase PhoR; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; Domain of unknown function (DUF3329); TIGRFAM: phosphate regulon sensor kinase PhoR. | 0.995 |
| EIC28639.1 | EIC28637.1 | Metal_0809 | Metal_0807 | Phosphate regulon sensor kinase PhoR; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; Domain of unknown function (DUF3329); TIGRFAM: phosphate regulon sensor kinase PhoR. | PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region. | 0.482 |
| EIC28639.1 | EIC28638.1 | Metal_0809 | Metal_0808 | Phosphate regulon sensor kinase PhoR; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; Domain of unknown function (DUF3329); TIGRFAM: phosphate regulon sensor kinase PhoR. | PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal; TIGRFAM: phosphate regulon transcriptional regulatory protein PhoB. | 0.995 |
| EIC28814.1 | EIC28637.1 | Metal_0995 | Metal_0807 | Exodeoxyribonuclease III; PFAM: Endonuclease/Exonuclease/phosphatase family; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III (xth). | PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region. | 0.776 |
| EIC28814.1 | birA | Metal_0995 | Metal_0899 | Exodeoxyribonuclease III; PFAM: Endonuclease/Exonuclease/phosphatase family; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III (xth). | birA, biotin-(acetyl-CoA-carboxylase) ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.918 |
| EIC30555.1 | EIC28637.1 | Metal_2868 | Metal_0807 | N-methylhydantoinase B/acetone carboxylase, alpha subunit; PFAM: Hydantoinase/oxoprolinase; Hydantoinase B/oxoprolinase; Hydantoinase/oxoprolinase N-terminal region. | PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region. | 0.710 |
| EIC30878.1 | EIC28637.1 | Metal_3207 | Metal_0807 | PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; TIGRFAM: S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region. | 0.535 |
| birA | EIC28637.1 | Metal_0899 | Metal_0807 | birA, biotin-(acetyl-CoA-carboxylase) ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region. | 0.887 |
| birA | EIC28814.1 | Metal_0899 | Metal_0995 | birA, biotin-(acetyl-CoA-carboxylase) ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Exodeoxyribonuclease III; PFAM: Endonuclease/Exonuclease/phosphatase family; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III (xth). | 0.918 |