Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EIC28742.1Multidrug resistance efflux pump; PFAM: HlyD family secretion protein. (356 aa)    
Predicted Functional Partners:
EIC28744.1
ABC-type multidrug transport system, permease component; PFAM: ABC-2 type transporter.
 
    0.961
EIC28743.1
ATPase component of various ABC-type transport systems with duplicated ATPase domain; PFAM: ABC transporter; ABC-2 type transporter.
  
 0.959
EIC28741.1
PFAM: Outer membrane efflux protein; TIGRFAM: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family.
  
  0.805
EIC28740.1
PFAM: Bacterial regulatory proteins, tetR family.
       0.705
EIC30282.1
Type I secretion system ATPase, LssB family; PFAM: ABC transporter; ABC transporter transmembrane region; TIGRFAM: type I secretion system ATPase, LssB family.
  
 0.676
EIC28789.1
ABC-type multidrug transport system, permease component; PFAM: ABC-2 type transporter.
 
  
 0.643
EIC28790.1
ABC-type multidrug transport system, ATPase component; PFAM: ABC transporter.
 
  
 0.623
EIC28738.1
PFAM: Major Facilitator Superfamily; TIGRFAM: drug resistance transporter, EmrB/QacA subfamily.
  
   0.592
macB
ABC-type antimicrobial peptide transport system, ATPase component; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
  
 0.583
EIC28788.1
ABC-type multidrug transport system, permease component; PFAM: ABC-2 type transporter.
 
  
 0.563
Your Current Organism:
Methylomicrobium album
NCBI taxonomy Id: 686340
Other names: M. album BG8, Methylomicrobium album BG8, Methylomicrobium album str. BG8, Methylomicrobium album strain BG8
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