Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EIC28887.15,10-methenyltetrahydrofolate synthetase; PFAM: 5-formyltetrahydrofolate cyclo-ligase family; TIGRFAM: 5,10-methenyltetrahydrofolate synthetase. (202 aa)    
Predicted Functional Partners:
EIC29186.1
Methenyl tetrahydrofolate cyclohydrolase; PFAM: Formiminotransferase-cyclodeaminase.
    
  0.905
EIC29741.1
Putative ornithine cyclodeaminase, mu-crystallin; PFAM: Methylene-tetrahydromethanopterin dehydrogenase, N-terminal.
     
  0.793
EIC28886.1
Diaminopimelate decarboxylase; Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine; Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
       0.773
EIC28888.1
glutamyl-tRNA reductase; PFAM: Methylene-tetrahydromethanopterin dehydrogenase, N-terminal.
    
  0.692
EIC28885.1
Zn-dependent oxidoreductase, NADPH:quinone reductase; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase.
       0.686
EIC28940.1
PFAM: Mur ligase middle domain; TIGRFAM: folylpolyglutamate synthase/dihydrofolate synthase; Belongs to the folylpolyglutamate synthase family.
    
 0.605
fhs
Formyltetrahydrofolate synthetase; PFAM: Formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family.
   
 0.583
EIC28889.1
PFAM: Methylene-tetrahydromethanopterin dehydrogenase, N-terminal.
    
  0.557
EIC28383.1
Putative membrane protein; PFAM: Rhomboid family.
  
  
 0.540
EIC30669.1
Putative membrane protein; PFAM: Rhomboid family.
  
  
 0.540
Your Current Organism:
Methylomicrobium album
NCBI taxonomy Id: 686340
Other names: M. album BG8, Methylomicrobium album BG8, Methylomicrobium album str. BG8, Methylomicrobium album strain BG8
Server load: low (16%) [HD]