STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EIC29463.1RraA family protein; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions. (179 aa)    
Predicted Functional Partners:
ispH
(E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
       0.715
EIC30826.1
6-phospho 3-hexuloisomerase/3-hexulose-6-phosphate synthase; PFAM: SIS domain; Orotidine 5'-phosphate decarboxylase / HUMPS family; TIGRFAM: 3-hexulose-6-phosphate synthase; 6-phospho 3-hexuloisomerase.
    
  0.713
EIC29461.1
Ribosome-associated heat shock protein implicated in recycling of 50S subunit; PFAM: S4 domain; Belongs to the HSP15 family.
       0.694
EIC31548.1
Putative TIM-barrel fold metal-dependent hydrolase; PFAM: Amidohydrolase.
    
 0.653
rhlB
DNA/RNA helicase, superfamily II; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily.
    
 
 0.563
EIC28811.1
DNA/RNA helicase, superfamily II; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; Belongs to the DEAD box helicase family.
    
 
 0.563
deaD
DNA/RNA helicase, superfamily II; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.
    
 
 0.563
EIC30746.1
DNA/RNA helicase, superfamily II; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; Belongs to the DEAD box helicase family.
    
 
 0.563
EIC29610.1
5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
 0.557
EIC28411.1
DNA/RNA helicase, superfamily II, SNF2 family; PFAM: Helicase conserved C-terminal domain; SNF2 family N-terminal domain.
    
 
 0.545
Your Current Organism:
Methylomicrobium album
NCBI taxonomy Id: 686340
Other names: M. album BG8, Methylomicrobium album BG8, Methylomicrobium album str. BG8, Methylomicrobium album strain BG8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.