| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EIC28819.1 | EIC29078.1 | Metal_1000 | Metal_1278 | PFAM: CDP-alcohol phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Amino acid adenylation enzyme/thioester reductase family protein; PFAM: Phosphopantetheine attachment site; AMP-binding enzyme; Condensation domain; TIGRFAM: amino acid adenylation domain. | 0.409 |
| EIC28819.1 | EIC29787.1 | Metal_1000 | Metal_2027 | PFAM: CDP-alcohol phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | PFAM: CDP-alcohol phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.772 |
| EIC28819.1 | EIC30128.1 | Metal_1000 | Metal_2405 | PFAM: CDP-alcohol phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | CDP-diglyceride synthetase; PFAM: Cytidylyltransferase family; Belongs to the CDS family. | 0.927 |
| EIC28819.1 | EIC30288.1 | Metal_1000 | Metal_2573 | PFAM: CDP-alcohol phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | PFAM: CDP-alcohol phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.872 |
| EIC28819.1 | psd | Metal_1000 | Metal_3171 | PFAM: CDP-alcohol phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Phosphatidylserine decarboxylase precursor; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). | 0.865 |
| EIC29078.1 | EIC28819.1 | Metal_1278 | Metal_1000 | Amino acid adenylation enzyme/thioester reductase family protein; PFAM: Phosphopantetheine attachment site; AMP-binding enzyme; Condensation domain; TIGRFAM: amino acid adenylation domain. | PFAM: CDP-alcohol phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.409 |
| EIC29078.1 | EIC29787.1 | Metal_1278 | Metal_2027 | Amino acid adenylation enzyme/thioester reductase family protein; PFAM: Phosphopantetheine attachment site; AMP-binding enzyme; Condensation domain; TIGRFAM: amino acid adenylation domain. | PFAM: CDP-alcohol phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.409 |
| EIC29078.1 | EIC30128.1 | Metal_1278 | Metal_2405 | Amino acid adenylation enzyme/thioester reductase family protein; PFAM: Phosphopantetheine attachment site; AMP-binding enzyme; Condensation domain; TIGRFAM: amino acid adenylation domain. | CDP-diglyceride synthetase; PFAM: Cytidylyltransferase family; Belongs to the CDS family. | 0.654 |
| EIC29078.1 | EIC30288.1 | Metal_1278 | Metal_2573 | Amino acid adenylation enzyme/thioester reductase family protein; PFAM: Phosphopantetheine attachment site; AMP-binding enzyme; Condensation domain; TIGRFAM: amino acid adenylation domain. | PFAM: CDP-alcohol phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.805 |
| EIC29078.1 | EIC30499.1 | Metal_1278 | Metal_2808 | Amino acid adenylation enzyme/thioester reductase family protein; PFAM: Phosphopantetheine attachment site; AMP-binding enzyme; Condensation domain; TIGRFAM: amino acid adenylation domain. | TIGRFAM: Haloacid Dehalogenase superfamily, subfamily IB, phosphoserine phosphatase-like. | 0.887 |
| EIC29078.1 | glyA | Metal_1278 | Metal_1974 | Amino acid adenylation enzyme/thioester reductase family protein; PFAM: Phosphopantetheine attachment site; AMP-binding enzyme; Condensation domain; TIGRFAM: amino acid adenylation domain. | Glycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.813 |
| EIC29078.1 | psd | Metal_1278 | Metal_3171 | Amino acid adenylation enzyme/thioester reductase family protein; PFAM: Phosphopantetheine attachment site; AMP-binding enzyme; Condensation domain; TIGRFAM: amino acid adenylation domain. | Phosphatidylserine decarboxylase precursor; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). | 0.746 |
| EIC29078.1 | trpA | Metal_1278 | Metal_1125 | Amino acid adenylation enzyme/thioester reductase family protein; PFAM: Phosphopantetheine attachment site; AMP-binding enzyme; Condensation domain; TIGRFAM: amino acid adenylation domain. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.823 |
| EIC29078.1 | trpB | Metal_1278 | Metal_1126 | Amino acid adenylation enzyme/thioester reductase family protein; PFAM: Phosphopantetheine attachment site; AMP-binding enzyme; Condensation domain; TIGRFAM: amino acid adenylation domain. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.820 |
| EIC29744.1 | EIC30288.1 | Metal_1979 | Metal_2573 | Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase; PFAM: Aminotransferase class-V. | PFAM: CDP-alcohol phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.793 |
| EIC29744.1 | EIC30499.1 | Metal_1979 | Metal_2808 | Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase; PFAM: Aminotransferase class-V. | TIGRFAM: Haloacid Dehalogenase superfamily, subfamily IB, phosphoserine phosphatase-like. | 0.842 |
| EIC29744.1 | glyA | Metal_1979 | Metal_1974 | Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase; PFAM: Aminotransferase class-V. | Glycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.862 |
| EIC29744.1 | trpA | Metal_1979 | Metal_1125 | Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase; PFAM: Aminotransferase class-V. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.821 |
| EIC29744.1 | trpB | Metal_1979 | Metal_1126 | Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase; PFAM: Aminotransferase class-V. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.809 |
| EIC29787.1 | EIC28819.1 | Metal_2027 | Metal_1000 | PFAM: CDP-alcohol phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | PFAM: CDP-alcohol phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.772 |