Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EIC30826.16-phospho 3-hexuloisomerase/3-hexulose-6-phosphate synthase; PFAM: SIS domain; Orotidine 5'-phosphate decarboxylase / HUMPS family; TIGRFAM: 3-hexulose-6-phosphate synthase; 6-phospho 3-hexuloisomerase. (405 aa)    
Predicted Functional Partners:
EIC31113.1
PFAM: SIS domain; TIGRFAM: 6-phospho 3-hexuloisomerase.
  
 
 0.929
EIC28103.1
KpsF/GutQ family protein; PFAM: CBS domain; SIS domain; TIGRFAM: KpsF/GutQ family protein.
  
 
 0.908
EIC31095.1
PFAM: Ribulose-phosphate 3 epimerase family; TIGRFAM: ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.
    
 0.864
pfp
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
    
 0.849
EIC31112.1
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
    
 0.849
EIC29338.1
PFAM: Ribose 5-phosphate isomerase A (phosphoriboisomerase A); Bacterial regulatory proteins, deoR family; TIGRFAM: ribose 5-phosphate isomerase.
  
 
 0.844
rpiA
Ribose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
  
 
 0.844
fbp
Fructose-1,6-bisphosphatase; PFAM: Fructose-1-6-bisphosphatase; Belongs to the FBPase class 1 family.
   
 
 0.804
EIC31114.1
3-hexulose-6-phosphate synthase; PFAM: Orotidine 5'-phosphate decarboxylase / HUMPS family; TIGRFAM: 3-hexulose-6-phosphate synthase.
  
 
 0.787
EIC30592.1
PFAM: Transketolase, thiamine diphosphate binding domain; Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain.
    
 0.760
Your Current Organism:
Methylomicrobium album
NCBI taxonomy Id: 686340
Other names: M. album BG8, Methylomicrobium album BG8, Methylomicrobium album str. BG8, Methylomicrobium album strain BG8
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