Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EIC31131.1Uncharacterized protein associated with GTPases; PFAM: Domain of unknown function (DUF697). (450 aa)    
Predicted Functional Partners:
EIC31130.1
Putative GTPase.
 
     0.953
ispG
1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.
       0.701
EIC31129.1
PFAM: Retroviral aspartyl protease; TIGRFAM: clan AA aspartic protease, TIGR02281 family.
       0.636
EIC31128.1
PFAM: Protein of unknown function (DUF2817).
 
     0.524
EIC31133.1
Putative phosphohydrolase; PFAM: Calcineurin-like phosphoesterase.
       0.502
EIC30538.1
PFAM: AhpC/TSA family.
  
     0.494
EIC30120.1
PFAM: Protein of unknown function (DUF1451).
  
     0.470
EIC31188.1
PFAM: FeoC like transcriptional regulator.
  
     0.452
EIC31127.1
PFAM: Acetyltransferase (GNAT) family; Domain of unknown function (DUF3335).
       0.442
EIC30494.1
Bacterioferritin (cytochrome b1); PFAM: Ferritin-like domain; Belongs to the Dps family.
  
     0.420
Your Current Organism:
Methylomicrobium album
NCBI taxonomy Id: 686340
Other names: M. album BG8, Methylomicrobium album BG8, Methylomicrobium album str. BG8, Methylomicrobium album strain BG8
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