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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EIC31174.1beta-RFAP synthase; PFAM: GHMP kinases C terminal; GHMP kinases N terminal domain; TIGRFAM: beta-RFAP synthase; manually curated. (320 aa)    
Predicted Functional Partners:
EIC31173.1
Putative ATP-dependent carboligase; PFAM: ATP-grasp domain.
 
     0.934
EIC31170.1
Triphosphoribosyl-dephospho-CoA synthetase; PFAM: ATP:dephospho-CoA triphosphoribosyl transferase.
 
     0.933
mch
Methenyltetrahydromethanopterin cyclohydrolase; Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl- H(4)MPT; Belongs to the MCH family.
 
     0.933
EIC31171.1
PFAM: RimK-like ATP-grasp domain; TIGRFAM: alpha-L-glutamate ligases, RimK family; Belongs to the RimK family.
 
     0.928
EIC31169.1
PFAM: Formaldehyde-activating enzyme (Fae); TIGRFAM: formaldehyde-activating enzyme.
 
     0.884
ffsA
Formylmethanofuran--tetrahydromethanopterin N-formyltransferase; Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT); Belongs to the FTR family.
 
     0.803
EIC28653.1
PFAM: Protein of unknown function (DUF447).
 
     0.803
EIC28259.1
TIGRFAM: formylmethanofuran dehydrogenase subunit B.
 
     0.801
EIC30286.1
PFAM: Flavoprotein.
 
    0.801
EIC28267.1
PFAM: GXGXG motif; TIGRFAM: formylmethanofuran dehydrogenase subunit C.
 
     0.800
Your Current Organism:
Methylomicrobium album
NCBI taxonomy Id: 686340
Other names: M. album BG8, Methylomicrobium album BG8, Methylomicrobium album str. BG8, Methylomicrobium album strain BG8
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