Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EIC31230.1Dinucleotide-utilizing enzyme possibly involved in molybdopterin or thiamin biosynthesis; PFAM: MoeZ/MoeB domain; ThiF family. (251 aa)    
Predicted Functional Partners:
thiG
Thiamine biosynthesis protein ThiS; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 0.999
EIC28730.1
Molybdopterin converting factor, large subunit; PFAM: MoaE protein.
 
 0.984
EIC28729.1
PFAM: ThiS family; TIGRFAM: molybdopterin converting factor, subunit 1, non-archaeal.
   
 0.983
EIC28894.1
Rhodanese-related sulfurtransferase; PFAM: Rhodanese-like domain.
  
 0.956
thiC
Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
  
 0.932
EIC30895.1
Cysteine desulfurase family protein; PFAM: Aminotransferase class-V.
   
 0.924
EIC29795.1
PFAM: Phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase.
 
  
 0.862
EIC31005.1
Putative metal-dependent protease of the PAD1/JAB1 superfamily; PFAM: Mov34/MPN/PAD-1 family.
 
 0.855
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
 
 0.821
EIC29789.1
Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
  
 0.766
Your Current Organism:
Methylomicrobium album
NCBI taxonomy Id: 686340
Other names: M. album BG8, Methylomicrobium album BG8, Methylomicrobium album str. BG8, Methylomicrobium album strain BG8
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