| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EIC28828.1 | EIC29027.1 | Metal_1009 | Metal_1218 | Beta-hydroxyacid dehydrogenase, 3-hydroxyisobutyrate dehydrogenase; PFAM: NAD binding domain of 6-phosphogluconate dehydrogenase. | Lactate dehydrogenase-like oxidoreductase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily. | 0.503 |
| EIC28828.1 | EIC29740.1 | Metal_1009 | Metal_1975 | Beta-hydroxyacid dehydrogenase, 3-hydroxyisobutyrate dehydrogenase; PFAM: NAD binding domain of 6-phosphogluconate dehydrogenase. | Putative glycerate kinase; PFAM: MOFRL family. | 0.641 |
| EIC28828.1 | EIC29743.1 | Metal_1009 | Metal_1978 | Beta-hydroxyacid dehydrogenase, 3-hydroxyisobutyrate dehydrogenase; PFAM: NAD binding domain of 6-phosphogluconate dehydrogenase. | Lactate dehydrogenase-like oxidoreductase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. | 0.563 |
| EIC28828.1 | EIC30498.1 | Metal_1009 | Metal_2807 | Beta-hydroxyacid dehydrogenase, 3-hydroxyisobutyrate dehydrogenase; PFAM: NAD binding domain of 6-phosphogluconate dehydrogenase. | PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; ACT domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, beta subunit; D-3-phosphoglycerate dehydrogenase. | 0.511 |
| EIC28828.1 | EIC31504.1 | Metal_1009 | Metal_3864 | Beta-hydroxyacid dehydrogenase, 3-hydroxyisobutyrate dehydrogenase; PFAM: NAD binding domain of 6-phosphogluconate dehydrogenase. | PFAM: Xylose isomerase-like TIM barrel; Belongs to the hyi family. | 0.856 |
| EIC29027.1 | EIC28828.1 | Metal_1218 | Metal_1009 | Lactate dehydrogenase-like oxidoreductase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily. | Beta-hydroxyacid dehydrogenase, 3-hydroxyisobutyrate dehydrogenase; PFAM: NAD binding domain of 6-phosphogluconate dehydrogenase. | 0.503 |
| EIC29027.1 | EIC29740.1 | Metal_1218 | Metal_1975 | Lactate dehydrogenase-like oxidoreductase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily. | Putative glycerate kinase; PFAM: MOFRL family. | 0.640 |
| EIC29027.1 | EIC29744.1 | Metal_1218 | Metal_1979 | Lactate dehydrogenase-like oxidoreductase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily. | Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase; PFAM: Aminotransferase class-V. | 0.705 |
| EIC29027.1 | EIC30498.1 | Metal_1218 | Metal_2807 | Lactate dehydrogenase-like oxidoreductase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily. | PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; ACT domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, beta subunit; D-3-phosphoglycerate dehydrogenase. | 0.653 |
| EIC29027.1 | EIC31503.1 | Metal_1218 | Metal_3863 | Lactate dehydrogenase-like oxidoreductase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily. | Beta-hydroxyacid dehydrogenase, 3-hydroxyisobutyrate dehydrogenase; PFAM: NAD binding domain of 6-phosphogluconate dehydrogenase. | 0.503 |
| EIC29027.1 | EIC31504.1 | Metal_1218 | Metal_3864 | Lactate dehydrogenase-like oxidoreductase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily. | PFAM: Xylose isomerase-like TIM barrel; Belongs to the hyi family. | 0.588 |
| EIC29119.1 | EIC29744.1 | Metal_1321 | Metal_1979 | glycine/D-amino acid oxidase, deaminating; PFAM: FAD dependent oxidoreductase. | Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase; PFAM: Aminotransferase class-V. | 0.661 |
| EIC29119.1 | EIC30498.1 | Metal_1321 | Metal_2807 | glycine/D-amino acid oxidase, deaminating; PFAM: FAD dependent oxidoreductase. | PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; ACT domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, beta subunit; D-3-phosphoglycerate dehydrogenase. | 0.407 |
| EIC29119.1 | EIC31504.1 | Metal_1321 | Metal_3864 | glycine/D-amino acid oxidase, deaminating; PFAM: FAD dependent oxidoreductase. | PFAM: Xylose isomerase-like TIM barrel; Belongs to the hyi family. | 0.450 |
| EIC29231.1 | EIC29744.1 | Metal_1446 | Metal_1979 | Glycine oxidase ThiO; PFAM: FAD dependent oxidoreductase; TIGRFAM: glycine oxidase ThiO. | Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase; PFAM: Aminotransferase class-V. | 0.661 |
| EIC29231.1 | EIC30498.1 | Metal_1446 | Metal_2807 | Glycine oxidase ThiO; PFAM: FAD dependent oxidoreductase; TIGRFAM: glycine oxidase ThiO. | PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; ACT domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, beta subunit; D-3-phosphoglycerate dehydrogenase. | 0.407 |
| EIC29231.1 | EIC31504.1 | Metal_1446 | Metal_3864 | Glycine oxidase ThiO; PFAM: FAD dependent oxidoreductase; TIGRFAM: glycine oxidase ThiO. | PFAM: Xylose isomerase-like TIM barrel; Belongs to the hyi family. | 0.455 |
| EIC29740.1 | EIC28828.1 | Metal_1975 | Metal_1009 | Putative glycerate kinase; PFAM: MOFRL family. | Beta-hydroxyacid dehydrogenase, 3-hydroxyisobutyrate dehydrogenase; PFAM: NAD binding domain of 6-phosphogluconate dehydrogenase. | 0.641 |
| EIC29740.1 | EIC29027.1 | Metal_1975 | Metal_1218 | Putative glycerate kinase; PFAM: MOFRL family. | Lactate dehydrogenase-like oxidoreductase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily. | 0.640 |
| EIC29740.1 | EIC29743.1 | Metal_1975 | Metal_1978 | Putative glycerate kinase; PFAM: MOFRL family. | Lactate dehydrogenase-like oxidoreductase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. | 0.837 |