STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
leuSleucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; Derived by automated computational [...] (872 aa)    
Predicted Functional Partners:
KIA80974.1
methionyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.999
KIA80707.1
isoleucine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
0.997
KIA81678.1
glutamyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.992
KIA80840.1
lysyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.990
KIA79302.1
arginyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.990
KIA82077.1
glutamyl-Q tRNA(Asp) ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.988
KIA81898.1
proline--tRNA ligase; Catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.988
KIA80968.1
glutaminyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.988
KIA81164.1
DNA topoisomerase I; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.987
KIA80338.1
phenylalanyl-tRNA synthetase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.978
Your Current Organism:
Chromobacterium piscinae
NCBI taxonomy Id: 686831
Other names: C. piscinae, CCM 3329, Chromobacterium piscinae Kampfer et al. 2009, LMG 3947, LMG:3947
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