STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A5C3LJB3DUF1767 domain-containing protein. (590 aa)    
Predicted Functional Partners:
A0A5C3M9J4
Uncharacterized protein.
    
 0.999
A0A5C3MFW6
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
    
 0.996
A0A5C3M9F4
Ribonuclease H-like domain-containing protein.
    
 0.994
A0A5C3MB29
Uncharacterized protein.
    
 0.955
A0A5C3MMS7
Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.
    
 0.955
A0A5C3MCD7
ERCC4 domain-containing protein.
    
 0.952
A0A5C3MC83
Uncharacterized protein.
    
 0.945
A0A5C3LM74
ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.
    
 0.926
A0A5C3LYR7
P-loop containing nucleoside triphosphate hydrolase protein.
    
 0.926
A0A5C3MD43
ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.
    
 0.926
Your Current Organism:
Crucibulum laeve
NCBI taxonomy Id: 68775
Other names: C. laeve
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.