STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A5C3LK37Peptidase family C54-domain-containing protein. (1106 aa)    
Predicted Functional Partners:
A0A5C3ME53
Autophagy-related protein.
   
 0.998
A0A5C3LIF0
Other/ULK/ULK protein kinase.
   
 
 0.982
A0A5C3M1F8
Alpha/Beta hydrolase protein.
   
 
 0.878
A0A5C3M449
Alpha/beta-hydrolase.
   
 
 0.878
A0A5C3M9Z3
Alpha/beta-hydrolase.
   
 
 0.878
A0A5C3LZV2
WD40 repeat-like protein.
   
 
 0.780
A0A5C3MG10
Uncharacterized protein.
   
 
 0.733
A0A5C3MHI6
Autophagy-related protein 3.
   
 
 0.733
A0A5C3LX33
Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...]
   
 
 0.732
A0A5C3MI19
Beclin 1 protein.
    
 
 0.654
Your Current Organism:
Crucibulum laeve
NCBI taxonomy Id: 68775
Other names: C. laeve
Server load: low (24%) [HD]