node1 | node2 | node1 annotation | node2 annotation | score |
A0A5C3LK34 | A0A5C3M7F3 | 3-oxo-5-alpha-steroid 4-dehydrogenase-domain-containing protein. | Delta 8-sphingoloid desaturase protein. | 0.768 |
A0A5C3LK34 | A0A5C3M7K3 | 3-oxo-5-alpha-steroid 4-dehydrogenase-domain-containing protein. | Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. | 0.912 |
A0A5C3LK34 | A0A5C3M846 | 3-oxo-5-alpha-steroid 4-dehydrogenase-domain-containing protein. | Ceramide very long chain fatty acid hydroxylase; Ceramide hydroxylase involved in the hydroxylation of sphingolipid-associated very long chain fatty acids. Postulated to hydroxylate the very long chain fatty acid of dihydroceramides and phytoceramides at C-2; Belongs to the sterol desaturase family. SCS7 subfamily. | 0.566 |
A0A5C3LK34 | A0A5C3M8H4 | 3-oxo-5-alpha-steroid 4-dehydrogenase-domain-containing protein. | Elongation of fatty acids protein. | 0.872 |
A0A5C3LK34 | A0A5C3M9V0 | 3-oxo-5-alpha-steroid 4-dehydrogenase-domain-containing protein. | Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. | 0.900 |
A0A5C3LK34 | A0A5C3MGD9 | 3-oxo-5-alpha-steroid 4-dehydrogenase-domain-containing protein. | Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids. | 0.977 |
A0A5C3LK34 | A0A5C3MGV9 | 3-oxo-5-alpha-steroid 4-dehydrogenase-domain-containing protein. | Uncharacterized protein. | 0.961 |
A0A5C3LK34 | A0A5C3MTC0 | 3-oxo-5-alpha-steroid 4-dehydrogenase-domain-containing protein. | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | 0.987 |
A0A5C3M4M0 | A0A5C3M8H4 | acidPPc domain-containing protein. | Elongation of fatty acids protein. | 0.736 |
A0A5C3M7F3 | A0A5C3LK34 | Delta 8-sphingoloid desaturase protein. | 3-oxo-5-alpha-steroid 4-dehydrogenase-domain-containing protein. | 0.768 |
A0A5C3M7F3 | A0A5C3M7K3 | Delta 8-sphingoloid desaturase protein. | Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. | 0.816 |
A0A5C3M7F3 | A0A5C3M846 | Delta 8-sphingoloid desaturase protein. | Ceramide very long chain fatty acid hydroxylase; Ceramide hydroxylase involved in the hydroxylation of sphingolipid-associated very long chain fatty acids. Postulated to hydroxylate the very long chain fatty acid of dihydroceramides and phytoceramides at C-2; Belongs to the sterol desaturase family. SCS7 subfamily. | 0.505 |
A0A5C3M7F3 | A0A5C3M8H4 | Delta 8-sphingoloid desaturase protein. | Elongation of fatty acids protein. | 0.826 |
A0A5C3M7F3 | A0A5C3M9V0 | Delta 8-sphingoloid desaturase protein. | Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. | 0.816 |
A0A5C3M7F3 | A0A5C3MGD9 | Delta 8-sphingoloid desaturase protein. | Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids. | 0.723 |
A0A5C3M7F3 | A0A5C3MGV9 | Delta 8-sphingoloid desaturase protein. | Uncharacterized protein. | 0.583 |
A0A5C3M7F3 | A0A5C3MTC0 | Delta 8-sphingoloid desaturase protein. | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | 0.583 |
A0A5C3M7K3 | A0A5C3LK34 | Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. | 3-oxo-5-alpha-steroid 4-dehydrogenase-domain-containing protein. | 0.912 |
A0A5C3M7K3 | A0A5C3M7F3 | Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. | Delta 8-sphingoloid desaturase protein. | 0.816 |
A0A5C3M7K3 | A0A5C3M846 | Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. | Ceramide very long chain fatty acid hydroxylase; Ceramide hydroxylase involved in the hydroxylation of sphingolipid-associated very long chain fatty acids. Postulated to hydroxylate the very long chain fatty acid of dihydroceramides and phytoceramides at C-2; Belongs to the sterol desaturase family. SCS7 subfamily. | 0.801 |