STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A5C3ME53Autophagy-related protein. (127 aa)    
Predicted Functional Partners:
A0A5C3LX33
Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...]
   
 0.999
A0A5C3MA97
Uncharacterized protein.
   
 0.999
A0A5C3LK37
Peptidase family C54-domain-containing protein.
   
 0.998
A0A5C3LIF0
Other/ULK/ULK protein kinase.
   
 0.997
A0A5C3MHI6
Autophagy-related protein 3.
  
 0.993
A0A5C3MG10
Uncharacterized protein.
   
 0.970
A0A5C3M3W8
Uncharacterized protein.
   
 0.951
A0A5C3MND1
FUN14 family-domain-containing protein.
    
 0.951
A0A5C3MI44
Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.
   
 0.930
A0A5C3MBR5
Rab-GTPase-TBC domain-containing protein.
   
 0.926
Your Current Organism:
Crucibulum laeve
NCBI taxonomy Id: 68775
Other names: C. laeve
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