node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
OCH17102.1 | OCH18703.1 | A6E04_19820 | A6E04_02435 | Coproporphyrinogen III oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Protoporphyrinogen oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.747 |
OCH17102.1 | OCH20273.1 | A6E04_19820 | A6E04_00925 | Coproporphyrinogen III oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | YggW family oxidoreductase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.737 |
OCH17102.1 | OCH21939.1 | A6E04_19820 | A6E04_08775 | Coproporphyrinogen III oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Putative heme utilization radical SAM enzyme HutW; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.582 |
OCH17102.1 | hemE | A6E04_19820 | A6E04_00110 | Coproporphyrinogen III oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.865 |
OCH18703.1 | OCH17102.1 | A6E04_02435 | A6E04_19820 | Protoporphyrinogen oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Coproporphyrinogen III oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.747 |
OCH18703.1 | OCH20273.1 | A6E04_02435 | A6E04_00925 | Protoporphyrinogen oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | YggW family oxidoreductase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.707 |
OCH18703.1 | OCH21939.1 | A6E04_02435 | A6E04_08775 | Protoporphyrinogen oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Putative heme utilization radical SAM enzyme HutW; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.601 |
OCH20273.1 | OCH17102.1 | A6E04_00925 | A6E04_19820 | YggW family oxidoreductase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Coproporphyrinogen III oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.737 |
OCH20273.1 | OCH18703.1 | A6E04_00925 | A6E04_02435 | YggW family oxidoreductase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Protoporphyrinogen oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.707 |
OCH20273.1 | OCH20274.1 | A6E04_00925 | A6E04_00930 | YggW family oxidoreductase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.917 |
OCH20273.1 | OCH20275.1 | A6E04_00925 | A6E04_00935 | YggW family oxidoreductase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.795 |
OCH20273.1 | OCH20276.1 | A6E04_00925 | A6E04_00940 | YggW family oxidoreductase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | YggU family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0235 family. | 0.718 |
OCH20273.1 | OCH20277.1 | A6E04_00925 | A6E04_00945 | YggW family oxidoreductase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.652 |
OCH20273.1 | OCH20279.1 | A6E04_00925 | A6E04_00955 | YggW family oxidoreductase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | YggS family pyridoxal phosphate enzyme; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.653 |
OCH20273.1 | OCH21939.1 | A6E04_00925 | A6E04_08775 | YggW family oxidoreductase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Putative heme utilization radical SAM enzyme HutW; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.634 |
OCH20273.1 | hemE | A6E04_00925 | A6E04_00110 | YggW family oxidoreductase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.792 |
OCH20273.1 | rlmN | A6E04_00925 | A6E04_14130 | YggW family oxidoreductase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Dual-specificity RNA methyltransferase RlmN; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. | 0.678 |
OCH20274.1 | OCH20273.1 | A6E04_00930 | A6E04_00925 | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | YggW family oxidoreductase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.917 |
OCH20274.1 | OCH20275.1 | A6E04_00930 | A6E04_00935 | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.917 |
OCH20274.1 | OCH20276.1 | A6E04_00930 | A6E04_00940 | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | YggU family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0235 family. | 0.718 |