| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| OCH20274.1 | OCH22017.1 | A6E04_00930 | A6E04_09180 | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.456 |
| OCH20274.1 | adk | A6E04_00930 | A6E04_13280 | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.742 |
| OCH20274.1 | guaA | A6E04_00930 | A6E04_14070 | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.930 |
| OCH20274.1 | guaB | A6E04_00930 | A6E04_14075 | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.856 |
| OCH21675.1 | OCH22017.1 | A6E04_07355 | A6E04_09180 | Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.525 |
| OCH22015.1 | OCH22016.1 | A6E04_09170 | A6E04_09175 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.475 |
| OCH22015.1 | OCH22017.1 | A6E04_09170 | A6E04_09180 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.475 |
| OCH22016.1 | OCH22015.1 | A6E04_09175 | A6E04_09170 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.475 |
| OCH22016.1 | OCH22017.1 | A6E04_09175 | A6E04_09180 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.779 |
| OCH22016.1 | OCH22018.1 | A6E04_09175 | A6E04_09185 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Penicillin-binding protein activator LpoB; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.438 |
| OCH22017.1 | OCH20274.1 | A6E04_09180 | A6E04_00930 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.456 |
| OCH22017.1 | OCH21675.1 | A6E04_09180 | A6E04_07355 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.525 |
| OCH22017.1 | OCH22015.1 | A6E04_09180 | A6E04_09170 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.475 |
| OCH22017.1 | OCH22016.1 | A6E04_09180 | A6E04_09175 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.779 |
| OCH22017.1 | OCH22018.1 | A6E04_09180 | A6E04_09185 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Penicillin-binding protein activator LpoB; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.438 |
| OCH22017.1 | adk | A6E04_09180 | A6E04_13280 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.485 |
| OCH22017.1 | guaA | A6E04_09180 | A6E04_14070 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.797 |
| OCH22017.1 | guaB | A6E04_09180 | A6E04_14075 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.753 |
| OCH22017.1 | tmk | A6E04_09180 | A6E04_10800 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.456 |
| OCH22017.1 | trpC | A6E04_09180 | A6E04_09725 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpC family. | 0.441 |