STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
purRTranscriptional repressor PurR; Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. (333 aa)    
Predicted Functional Partners:
OCH20392.1
Glutamate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.890
OCH17040.1
PTS glucose transporter subunit IIBC; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.840
OCH22038.1
PTS N-acetylmuramic acid transporter subunits IIBC; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.682
OCH22319.1
PTS glucose transporter subunit IIBC; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.682
OCH20742.1
PTS glucose transporter subunit IIBC; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.682
OCH17184.1
PTS trehalose transporter subunit IIBC; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.682
OCH21640.1
Ribose ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family.
 
 
 0.546
rbsA
Ribose ABC transporter ATP-binding protein RbsA; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.
 
 
 0.530
OCH23221.1
Bifunctional PTS fructose transporter subunit IIA/HPr protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.506
OCH20582.1
PTS sugar transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
   0.492
Your Current Organism:
Aliivibrio logei
NCBI taxonomy Id: 688
Other names: A. logei, ATCC 29985, CCUG 20283, CIP 104991, LMG 21012, LMG:21012, NCIMB 2252, Photobacterium logei, Vibrio logei, strain 584
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.