| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EGN56204.1 | EGN56205.1 | Premu_0742 | Premu_0743 | Amino acid carrier protein; COGs: COG1115 Na+/alanine symporter; InterPro IPR001463; KEGG: pru:PRU_1855 alanine or glycine:cation symporter (AGCS) family transporter; PFAM: Sodium:alanine symporter; SPTR: Amino acid carrier protein; TIGRFAM: Sodium:alanine symporter; IMG reference gene:2503874772; PFAM: Sodium:alanine symporter family; TIGRFAM: amino acid carrier protein. | Protein of unknown function DUF303 acetylesterase; InterPro IPR005181; KEGG: pru:PRU_2629 sialic acid-specific 9-O-acetylesterase-like protein; PFAM: Domain of unknown function DUF303, acetylesterase putative; SPTR: Sialic acid-specific 9-O-acetylesterase; IMG reference gene:2503874773; PFAM: Domain of unknown function (DUF303). | 0.598 |
| EGN56204.1 | EGN56610.1 | Premu_0742 | Premu_1177 | Amino acid carrier protein; COGs: COG1115 Na+/alanine symporter; InterPro IPR001463; KEGG: pru:PRU_1855 alanine or glycine:cation symporter (AGCS) family transporter; PFAM: Sodium:alanine symporter; SPTR: Amino acid carrier protein; TIGRFAM: Sodium:alanine symporter; IMG reference gene:2503874772; PFAM: Sodium:alanine symporter family; TIGRFAM: amino acid carrier protein. | CDP-alcohol phosphatidyltransferase; COGs: COG1183 Phosphatidylserine synthase; InterPro IPR000462; KEGG: pmz:HMPREF0659_A5449 CDP-diacylglycerol-serine O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; SPTR: CDP-diacylglycerol-serine O-phosphatidyltransferase; IMG reference gene:2503875216; PFAM: CDP-alcohol phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.461 |
| EGN56204.1 | EGN56788.1 | Premu_0742 | Premu_1359 | Amino acid carrier protein; COGs: COG1115 Na+/alanine symporter; InterPro IPR001463; KEGG: pru:PRU_1855 alanine or glycine:cation symporter (AGCS) family transporter; PFAM: Sodium:alanine symporter; SPTR: Amino acid carrier protein; TIGRFAM: Sodium:alanine symporter; IMG reference gene:2503874772; PFAM: Sodium:alanine symporter family; TIGRFAM: amino acid carrier protein. | Cl- channel voltage-gated family protein; COGs: COG0038 Chloride channel protein EriC; InterPro IPR000644:IPR001807; KEGG: pmz:HMPREF0659_A5914 chloride transporter, ClC family; PFAM: Chloride channel, voltage gated; Cystathionine beta-synthase, core; SMART: Cystathionine beta-synthase, core; SPTR: Putative uncharacterized protein; IMG reference gene:2503875403; PFAM: CBS domain; Voltage gated chloride channel. | 0.475 |
| EGN56204.1 | EGN56827.1 | Premu_0742 | Premu_1399 | Amino acid carrier protein; COGs: COG1115 Na+/alanine symporter; InterPro IPR001463; KEGG: pru:PRU_1855 alanine or glycine:cation symporter (AGCS) family transporter; PFAM: Sodium:alanine symporter; SPTR: Amino acid carrier protein; TIGRFAM: Sodium:alanine symporter; IMG reference gene:2503874772; PFAM: Sodium:alanine symporter family; TIGRFAM: amino acid carrier protein. | Hypothetical protein; KEGG: pmz:HMPREF0659_A5984 transporter, dicarboxylate/amino acid:cation Na+/H+ symporter family protein; SPTR: Na+/H+-dicarboxylate symporter; IMG reference gene:2503875443. | 0.436 |
| EGN56204.1 | sucC | Premu_0742 | Premu_0744 | Amino acid carrier protein; COGs: COG1115 Na+/alanine symporter; InterPro IPR001463; KEGG: pru:PRU_1855 alanine or glycine:cation symporter (AGCS) family transporter; PFAM: Sodium:alanine symporter; SPTR: Amino acid carrier protein; TIGRFAM: Sodium:alanine symporter; IMG reference gene:2503874772; PFAM: Sodium:alanine symporter family; TIGRFAM: amino acid carrier protein. | succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.489 |
| EGN56204.1 | sucD | Premu_0742 | Premu_0745 | Amino acid carrier protein; COGs: COG1115 Na+/alanine symporter; InterPro IPR001463; KEGG: pru:PRU_1855 alanine or glycine:cation symporter (AGCS) family transporter; PFAM: Sodium:alanine symporter; SPTR: Amino acid carrier protein; TIGRFAM: Sodium:alanine symporter; IMG reference gene:2503874772; PFAM: Sodium:alanine symporter family; TIGRFAM: amino acid carrier protein. | succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.451 |
| EGN56205.1 | EGN56204.1 | Premu_0743 | Premu_0742 | Protein of unknown function DUF303 acetylesterase; InterPro IPR005181; KEGG: pru:PRU_2629 sialic acid-specific 9-O-acetylesterase-like protein; PFAM: Domain of unknown function DUF303, acetylesterase putative; SPTR: Sialic acid-specific 9-O-acetylesterase; IMG reference gene:2503874773; PFAM: Domain of unknown function (DUF303). | Amino acid carrier protein; COGs: COG1115 Na+/alanine symporter; InterPro IPR001463; KEGG: pru:PRU_1855 alanine or glycine:cation symporter (AGCS) family transporter; PFAM: Sodium:alanine symporter; SPTR: Amino acid carrier protein; TIGRFAM: Sodium:alanine symporter; IMG reference gene:2503874772; PFAM: Sodium:alanine symporter family; TIGRFAM: amino acid carrier protein. | 0.598 |
| EGN56205.1 | sucC | Premu_0743 | Premu_0744 | Protein of unknown function DUF303 acetylesterase; InterPro IPR005181; KEGG: pru:PRU_2629 sialic acid-specific 9-O-acetylesterase-like protein; PFAM: Domain of unknown function DUF303, acetylesterase putative; SPTR: Sialic acid-specific 9-O-acetylesterase; IMG reference gene:2503874773; PFAM: Domain of unknown function (DUF303). | succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.625 |
| EGN56205.1 | sucD | Premu_0743 | Premu_0745 | Protein of unknown function DUF303 acetylesterase; InterPro IPR005181; KEGG: pru:PRU_2629 sialic acid-specific 9-O-acetylesterase-like protein; PFAM: Domain of unknown function DUF303, acetylesterase putative; SPTR: Sialic acid-specific 9-O-acetylesterase; IMG reference gene:2503874773; PFAM: Domain of unknown function (DUF303). | succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.571 |
| EGN56610.1 | EGN56204.1 | Premu_1177 | Premu_0742 | CDP-alcohol phosphatidyltransferase; COGs: COG1183 Phosphatidylserine synthase; InterPro IPR000462; KEGG: pmz:HMPREF0659_A5449 CDP-diacylglycerol-serine O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; SPTR: CDP-diacylglycerol-serine O-phosphatidyltransferase; IMG reference gene:2503875216; PFAM: CDP-alcohol phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Amino acid carrier protein; COGs: COG1115 Na+/alanine symporter; InterPro IPR001463; KEGG: pru:PRU_1855 alanine or glycine:cation symporter (AGCS) family transporter; PFAM: Sodium:alanine symporter; SPTR: Amino acid carrier protein; TIGRFAM: Sodium:alanine symporter; IMG reference gene:2503874772; PFAM: Sodium:alanine symporter family; TIGRFAM: amino acid carrier protein. | 0.461 |
| EGN56788.1 | EGN56204.1 | Premu_1359 | Premu_0742 | Cl- channel voltage-gated family protein; COGs: COG0038 Chloride channel protein EriC; InterPro IPR000644:IPR001807; KEGG: pmz:HMPREF0659_A5914 chloride transporter, ClC family; PFAM: Chloride channel, voltage gated; Cystathionine beta-synthase, core; SMART: Cystathionine beta-synthase, core; SPTR: Putative uncharacterized protein; IMG reference gene:2503875403; PFAM: CBS domain; Voltage gated chloride channel. | Amino acid carrier protein; COGs: COG1115 Na+/alanine symporter; InterPro IPR001463; KEGG: pru:PRU_1855 alanine or glycine:cation symporter (AGCS) family transporter; PFAM: Sodium:alanine symporter; SPTR: Amino acid carrier protein; TIGRFAM: Sodium:alanine symporter; IMG reference gene:2503874772; PFAM: Sodium:alanine symporter family; TIGRFAM: amino acid carrier protein. | 0.475 |
| EGN56827.1 | EGN56204.1 | Premu_1399 | Premu_0742 | Hypothetical protein; KEGG: pmz:HMPREF0659_A5984 transporter, dicarboxylate/amino acid:cation Na+/H+ symporter family protein; SPTR: Na+/H+-dicarboxylate symporter; IMG reference gene:2503875443. | Amino acid carrier protein; COGs: COG1115 Na+/alanine symporter; InterPro IPR001463; KEGG: pru:PRU_1855 alanine or glycine:cation symporter (AGCS) family transporter; PFAM: Sodium:alanine symporter; SPTR: Amino acid carrier protein; TIGRFAM: Sodium:alanine symporter; IMG reference gene:2503874772; PFAM: Sodium:alanine symporter family; TIGRFAM: amino acid carrier protein. | 0.436 |
| sucC | EGN56204.1 | Premu_0744 | Premu_0742 | succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | Amino acid carrier protein; COGs: COG1115 Na+/alanine symporter; InterPro IPR001463; KEGG: pru:PRU_1855 alanine or glycine:cation symporter (AGCS) family transporter; PFAM: Sodium:alanine symporter; SPTR: Amino acid carrier protein; TIGRFAM: Sodium:alanine symporter; IMG reference gene:2503874772; PFAM: Sodium:alanine symporter family; TIGRFAM: amino acid carrier protein. | 0.489 |
| sucC | EGN56205.1 | Premu_0744 | Premu_0743 | succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | Protein of unknown function DUF303 acetylesterase; InterPro IPR005181; KEGG: pru:PRU_2629 sialic acid-specific 9-O-acetylesterase-like protein; PFAM: Domain of unknown function DUF303, acetylesterase putative; SPTR: Sialic acid-specific 9-O-acetylesterase; IMG reference gene:2503874773; PFAM: Domain of unknown function (DUF303). | 0.625 |
| sucC | sucD | Premu_0744 | Premu_0745 | succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.999 |
| sucD | EGN56204.1 | Premu_0745 | Premu_0742 | succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | Amino acid carrier protein; COGs: COG1115 Na+/alanine symporter; InterPro IPR001463; KEGG: pru:PRU_1855 alanine or glycine:cation symporter (AGCS) family transporter; PFAM: Sodium:alanine symporter; SPTR: Amino acid carrier protein; TIGRFAM: Sodium:alanine symporter; IMG reference gene:2503874772; PFAM: Sodium:alanine symporter family; TIGRFAM: amino acid carrier protein. | 0.451 |
| sucD | EGN56205.1 | Premu_0745 | Premu_0743 | succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | Protein of unknown function DUF303 acetylesterase; InterPro IPR005181; KEGG: pru:PRU_2629 sialic acid-specific 9-O-acetylesterase-like protein; PFAM: Domain of unknown function DUF303, acetylesterase putative; SPTR: Sialic acid-specific 9-O-acetylesterase; IMG reference gene:2503874773; PFAM: Domain of unknown function (DUF303). | 0.571 |
| sucD | sucC | Premu_0745 | Premu_0744 | succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.999 |