Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EGN56204.1Amino acid carrier protein; COGs: COG1115 Na+/alanine symporter; InterPro IPR001463; KEGG: pru:PRU_1855 alanine or glycine:cation symporter (AGCS) family transporter; PFAM: Sodium:alanine symporter; SPTR: Amino acid carrier protein; TIGRFAM: Sodium:alanine symporter; IMG reference gene:2503874772; PFAM: Sodium:alanine symporter family; TIGRFAM: amino acid carrier protein. (458 aa)    
Predicted Functional Partners:
EGN56205.1
Protein of unknown function DUF303 acetylesterase; InterPro IPR005181; KEGG: pru:PRU_2629 sialic acid-specific 9-O-acetylesterase-like protein; PFAM: Domain of unknown function DUF303, acetylesterase putative; SPTR: Sialic acid-specific 9-O-acetylesterase; IMG reference gene:2503874773; PFAM: Domain of unknown function (DUF303).
       0.598
sucC
succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
       0.489
EGN56788.1
Cl- channel voltage-gated family protein; COGs: COG0038 Chloride channel protein EriC; InterPro IPR000644:IPR001807; KEGG: pmz:HMPREF0659_A5914 chloride transporter, ClC family; PFAM: Chloride channel, voltage gated; Cystathionine beta-synthase, core; SMART: Cystathionine beta-synthase, core; SPTR: Putative uncharacterized protein; IMG reference gene:2503875403; PFAM: CBS domain; Voltage gated chloride channel.
  
    0.475
EGN56610.1
CDP-alcohol phosphatidyltransferase; COGs: COG1183 Phosphatidylserine synthase; InterPro IPR000462; KEGG: pmz:HMPREF0659_A5449 CDP-diacylglycerol-serine O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; SPTR: CDP-diacylglycerol-serine O-phosphatidyltransferase; IMG reference gene:2503875216; PFAM: CDP-alcohol phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
    
  0.461
sucD
succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
       0.451
EGN56827.1
Hypothetical protein; KEGG: pmz:HMPREF0659_A5984 transporter, dicarboxylate/amino acid:cation Na+/H+ symporter family protein; SPTR: Na+/H+-dicarboxylate symporter; IMG reference gene:2503875443.
 
   
 0.436
Your Current Organism:
Prevotella multisaccharivorax
NCBI taxonomy Id: 688246
Other names: P. multisaccharivorax DSM 17128, Prevotella multisaccharivorax DSM 17128, Prevotella multisaccharivorax JCM 12954, Prevotella multisaccharivorax str. DSM 17128, Prevotella multisaccharivorax strain DSM 17128
Server load: low (38%) [HD]