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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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[Homology]
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EGN56466.1COGs: COG0686 Alanine dehydrogenase; InterPro IPR008141:IPR007886:IPR007698; KEGG: pru:PRU_2067 alanine dehydrogenase; PFAM: Alanine dehydrogenase/PNT, C-terminal; Alanine dehydrogenase/PNT, N-terminal; PRIAM: Alanine dehydrogenase; SPTR: Alanine dehydrogenase; TIGRFAM: Alanine dehydrogenase/pyridine nucleotide transhydrogenase; IMG reference gene:2503875062; PFAM: Alanine dehydrogenase/PNT, C-terminal domain; Alanine dehydrogenase/PNT, N-terminal domain; TIGRFAM: alanine dehydrogenase; Belongs to the AlaDH/PNT family. (368 aa)    
Predicted Functional Partners:
EGN57391.1
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
  
 
 0.917
EGN56623.1
COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895:IPR019456:IPR002880:IPR019752:IPR 001450:IPR011766; KEGG: pmz:HMPREF0659_A5561 pyruvate synthase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; 4Fe-4S binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: Pyruvate dehydrogenase (NADP(+)); SMART: Pyruvate-flavodoxin oxidoreductase, EKR domain; SPTR: Pyruvate-fla [...]
     
 0.886
nadK
Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
    
  0.728
nadE
NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
 
  0.727
EGN58144.1
COGs: COG0281 Malic enzyme; InterPro IPR012301:IPR012302:IPR002505; KEGG: pmz:HMPREF0659_A6863 malate dehydrogenase (oxaloacetate-decarboxylating); PFAM: Malic enzyme, NAD-binding; Malic enzyme, N-terminal; Phosphate acetyl/butaryl transferase; SMART: Malic enzyme, NAD-binding; SPTR: NADP-dependent malic enzyme; manually curated; IMG reference gene:2503876876; PFAM: Malic enzyme, NAD binding domain; Phosphate acetyl/butaryl transferase; Malic enzyme, N-terminal domain.
  
 
 0.723
EGN57374.1
2-oxoacid:acceptor oxidoreductase, alpha subunit; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR002880:IPR022367; KEGG: pmz:HMPREF0659_A6381 2-oxoacid:acceptor oxidoreductase, alpha subunit; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; PRIAM: 2-oxoglutarate synthase; SPTR: Pyruvate synthase; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, alpha subunit; IMG reference gene:2503876034; PFAM: domain; Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, alpha [...]
     
 0.719
EGN56765.1
COGs: COG0469 Pyruvate kinase; InterPro IPR001697:IPR015793:IPR015795; KEGG: pru:PRU_0684 pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, C-terminal-like; PRIAM: Pyruvate kinase; SPTR: Pyruvate kinase; TIGRFAM: Pyruvate kinase; IMG reference gene:2503875378; PFAM: Pyruvate kinase, barrel domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family.
     
 0.706
EGN56989.1
Pyruvate phosphate dikinase; COGs: COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; InterPro IPR010121:IPR002192:IPR008279:IPR000121; KEGG: pmz:HMPREF0659_A5567 pyruvate, phosphate dikinase; PFAM: Pyruvate phosphate dikinase, PEP/pyruvate-binding; PEP-utilising enzyme, mobile domain; PEP-utilising enzyme; PRIAM: Pyruvate, phosphate dikinase; SPTR: Pyruvate, phosphate dikinase; TIGRFAM: Pyruvate, phosphate dikinase; IMG reference gene:2503875622; PFAM: PEP-utilising enzyme, TIM barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate phosphate dikinase, PEP/pyruvate [...]
     
 0.679
EGN55703.1
3-methyl-2-oxobutanoate dehydrogenase (ferredoxin); COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR002880:IPR005476; KEGG: pmz:HMPREF0659_A5966 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin); PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Transketolase, C-terminal; PRIAM: 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin); SPTR: 2-oxoglutarate oxidoreductase beta subunit; IMG reference gene:2503874226; PFAM: domain; Transketolase, C-terminal domain.
     
 0.658
EGN57375.1
2-oxoglutarate synthase; COGs: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase beta subunit; InterPro IPR011766; KEGG: pmz:HMPREF0659_A6380 2-oxoglutarate ferredoxin oxidoreductase subunit beta; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: 2-oxoglutarate synthase; SPTR: 2-oxoglutarate ferredoxin oxidoreductase subunit beta; IMG reference gene:2503876035; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain.
     
 0.658
Your Current Organism:
Prevotella multisaccharivorax
NCBI taxonomy Id: 688246
Other names: P. multisaccharivorax DSM 17128, Prevotella multisaccharivorax DSM 17128, Prevotella multisaccharivorax JCM 12954, Prevotella multisaccharivorax str. DSM 17128, Prevotella multisaccharivorax strain DSM 17128
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