| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EGN55627.1 | EGN55628.1 | Premu_0136 | Premu_0137 | COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR004843; KEGG: pmz:HMPREF0659_A5395 Ser/Thr phosphatase family protein; PFAM: Metallo-dependent phosphatase; PRIAM: 5'-nucleotidase; SPTR: Putative uncharacterized protein; IMG reference gene:2503874142; PFAM: Calcineurin-like phosphoesterase. | 5'-Nucleotidase domain-containing protein; COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR008334; KEGG: pmz:HMPREF0659_A5394 5'-nucleotidase, C-terminal domain protein; PFAM: 5'-Nucleotidase, C-terminal; SPTR: 5-nucleotidase family protein; IMG reference gene:2503874143; PFAM: 5'-nucleotidase, C-terminal domain. | 0.941 |
| EGN55627.1 | EGN56087.1 | Premu_0136 | Premu_0611 | COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR004843; KEGG: pmz:HMPREF0659_A5395 Ser/Thr phosphatase family protein; PFAM: Metallo-dependent phosphatase; PRIAM: 5'-nucleotidase; SPTR: Putative uncharacterized protein; IMG reference gene:2503874142; PFAM: Calcineurin-like phosphoesterase. | COGs: COG0572 Uridine kinase; InterPro IPR006083; KEGG: pmz:HMPREF0659_A6356 phosphoribulokinase/uridine kinase family protein; PFAM: Phosphoribulokinase/uridine kinase; SPTR: Phosphoribulokinase family protein; IMG reference gene:2503874638; PFAM: Phosphoribulokinase / Uridine kinase family. | 0.721 |
| EGN55627.1 | EGN56656.1 | Premu_0136 | Premu_1227 | COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR004843; KEGG: pmz:HMPREF0659_A5395 Ser/Thr phosphatase family protein; PFAM: Metallo-dependent phosphatase; PRIAM: 5'-nucleotidase; SPTR: Putative uncharacterized protein; IMG reference gene:2503874142; PFAM: Calcineurin-like phosphoesterase. | NAD(+) diphosphatase; COGs: COG2816 NTP pyrophosphohydrolase containing a Zn-finger probably nucleic-acid-binding; InterPro IPR015375:IPR015376:IPR000086; KEGG: pmz:HMPREF0659_A5588 hydrolase, NUDIX family; PFAM: NUDIX hydrolase domain; Zinc ribbon, NADH pyrophosphatase; NADH pyrophosphatase-like, N-terminal; PRIAM: NAD(+) diphosphatase; SPTR: NAD(+) diphosphatase; IMG reference gene:2503875268; PFAM: NADH pyrophosphatase zinc ribbon domain; NUDIX domain. | 0.732 |
| EGN55627.1 | EGN56657.1 | Premu_0136 | Premu_1228 | COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR004843; KEGG: pmz:HMPREF0659_A5395 Ser/Thr phosphatase family protein; PFAM: Metallo-dependent phosphatase; PRIAM: 5'-nucleotidase; SPTR: Putative uncharacterized protein; IMG reference gene:2503874142; PFAM: Calcineurin-like phosphoesterase. | 2',3'-cyclic-nucleotide 2'-phosphodiesterase; COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR004843:IPR008334; KEGG: pmz:HMPREF0659_A5589 5'-nucleotidase, C-terminal domain protein; PFAM: Metallo-dependent phosphatase; 5'-Nucleotidase, C-terminal; PRIAM: 2',3'-cyclic-nucleotide 2'-phosphodiesterase; SPTR: 5'-nucleotidase; IMG reference gene:2503875269; PFAM: 5'-nucleotidase, C-terminal domain; Calcineurin-like phosphoesterase; Belongs to the 5'-nucleotidase family. | 0.786 |
| EGN55627.1 | EGN56664.1 | Premu_0136 | Premu_1235 | COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR004843; KEGG: pmz:HMPREF0659_A5395 Ser/Thr phosphatase family protein; PFAM: Metallo-dependent phosphatase; PRIAM: 5'-nucleotidase; SPTR: Putative uncharacterized protein; IMG reference gene:2503874142; PFAM: Calcineurin-like phosphoesterase. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.757 |
| EGN55627.1 | EGN57102.1 | Premu_0136 | Premu_1697 | COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR004843; KEGG: pmz:HMPREF0659_A5395 Ser/Thr phosphatase family protein; PFAM: Metallo-dependent phosphatase; PRIAM: 5'-nucleotidase; SPTR: Putative uncharacterized protein; IMG reference gene:2503874142; PFAM: Calcineurin-like phosphoesterase. | Inosine guanosine and xanthosine phosphorylase family; COGs: COG0005 Purine nucleoside phosphorylase; InterPro IPR011268:IPR000845; KEGG: pmz:HMPREF0659_A5845 purine nucleoside phosphorylase I, inosine and guanosine-specific; PFAM: Nucleoside phosphorylase domain; PRIAM: Purine-nucleoside phosphorylase; SPTR: Purine nucleoside phosphorylase I, inosine and guanosine-specific; TIGRFAM: Inosine guanosine/xanthosine phosphorylase; IMG reference gene:2503875743; PFAM: Phosphorylase superfamily; TIGRFAM: inosine guanosine and xanthosine phosphorylase family. | 0.718 |
| EGN55627.1 | guaB | Premu_0136 | Premu_0960 | COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR004843; KEGG: pmz:HMPREF0659_A5395 Ser/Thr phosphatase family protein; PFAM: Metallo-dependent phosphatase; PRIAM: 5'-nucleotidase; SPTR: Putative uncharacterized protein; IMG reference gene:2503874142; PFAM: Calcineurin-like phosphoesterase. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.777 |
| EGN55627.1 | surE | Premu_0136 | Premu_2585 | COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR004843; KEGG: pmz:HMPREF0659_A5395 Ser/Thr phosphatase family protein; PFAM: Metallo-dependent phosphatase; PRIAM: 5'-nucleotidase; SPTR: Putative uncharacterized protein; IMG reference gene:2503874142; PFAM: Calcineurin-like phosphoesterase. | 5'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.729 |
| EGN55627.1 | udk | Premu_0136 | Premu_2148 | COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR004843; KEGG: pmz:HMPREF0659_A5395 Ser/Thr phosphatase family protein; PFAM: Metallo-dependent phosphatase; PRIAM: 5'-nucleotidase; SPTR: Putative uncharacterized protein; IMG reference gene:2503874142; PFAM: Calcineurin-like phosphoesterase. | COGs: COG0572 Uridine kinase; HAMAP: Uridine kinase; InterPro IPR006083:IPR000764:IPR003593; KEGG: pmz:HMPREF0659_A7128 uridine kinase; PFAM: Phosphoribulokinase/uridine kinase; SMART: ATPase, AAA+ type, core; SPTR: Uridine kinase; TIGRFAM: Uridine kinase; IMG reference gene:2503876208; PFAM: Phosphoribulokinase / Uridine kinase family; TIGRFAM: uridine kinase. | 0.759 |
| EGN55628.1 | EGN55627.1 | Premu_0137 | Premu_0136 | 5'-Nucleotidase domain-containing protein; COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR008334; KEGG: pmz:HMPREF0659_A5394 5'-nucleotidase, C-terminal domain protein; PFAM: 5'-Nucleotidase, C-terminal; SPTR: 5-nucleotidase family protein; IMG reference gene:2503874143; PFAM: 5'-nucleotidase, C-terminal domain. | COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR004843; KEGG: pmz:HMPREF0659_A5395 Ser/Thr phosphatase family protein; PFAM: Metallo-dependent phosphatase; PRIAM: 5'-nucleotidase; SPTR: Putative uncharacterized protein; IMG reference gene:2503874142; PFAM: Calcineurin-like phosphoesterase. | 0.941 |
| EGN55628.1 | EGN56657.1 | Premu_0137 | Premu_1228 | 5'-Nucleotidase domain-containing protein; COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR008334; KEGG: pmz:HMPREF0659_A5394 5'-nucleotidase, C-terminal domain protein; PFAM: 5'-Nucleotidase, C-terminal; SPTR: 5-nucleotidase family protein; IMG reference gene:2503874143; PFAM: 5'-nucleotidase, C-terminal domain. | 2',3'-cyclic-nucleotide 2'-phosphodiesterase; COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR004843:IPR008334; KEGG: pmz:HMPREF0659_A5589 5'-nucleotidase, C-terminal domain protein; PFAM: Metallo-dependent phosphatase; 5'-Nucleotidase, C-terminal; PRIAM: 2',3'-cyclic-nucleotide 2'-phosphodiesterase; SPTR: 5'-nucleotidase; IMG reference gene:2503875269; PFAM: 5'-nucleotidase, C-terminal domain; Calcineurin-like phosphoesterase; Belongs to the 5'-nucleotidase family. | 0.779 |
| EGN55628.1 | guaB | Premu_0137 | Premu_0960 | 5'-Nucleotidase domain-containing protein; COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR008334; KEGG: pmz:HMPREF0659_A5394 5'-nucleotidase, C-terminal domain protein; PFAM: 5'-Nucleotidase, C-terminal; SPTR: 5-nucleotidase family protein; IMG reference gene:2503874143; PFAM: 5'-nucleotidase, C-terminal domain. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.691 |
| EGN56087.1 | EGN55627.1 | Premu_0611 | Premu_0136 | COGs: COG0572 Uridine kinase; InterPro IPR006083; KEGG: pmz:HMPREF0659_A6356 phosphoribulokinase/uridine kinase family protein; PFAM: Phosphoribulokinase/uridine kinase; SPTR: Phosphoribulokinase family protein; IMG reference gene:2503874638; PFAM: Phosphoribulokinase / Uridine kinase family. | COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR004843; KEGG: pmz:HMPREF0659_A5395 Ser/Thr phosphatase family protein; PFAM: Metallo-dependent phosphatase; PRIAM: 5'-nucleotidase; SPTR: Putative uncharacterized protein; IMG reference gene:2503874142; PFAM: Calcineurin-like phosphoesterase. | 0.721 |
| EGN56087.1 | EGN56657.1 | Premu_0611 | Premu_1228 | COGs: COG0572 Uridine kinase; InterPro IPR006083; KEGG: pmz:HMPREF0659_A6356 phosphoribulokinase/uridine kinase family protein; PFAM: Phosphoribulokinase/uridine kinase; SPTR: Phosphoribulokinase family protein; IMG reference gene:2503874638; PFAM: Phosphoribulokinase / Uridine kinase family. | 2',3'-cyclic-nucleotide 2'-phosphodiesterase; COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR004843:IPR008334; KEGG: pmz:HMPREF0659_A5589 5'-nucleotidase, C-terminal domain protein; PFAM: Metallo-dependent phosphatase; 5'-Nucleotidase, C-terminal; PRIAM: 2',3'-cyclic-nucleotide 2'-phosphodiesterase; SPTR: 5'-nucleotidase; IMG reference gene:2503875269; PFAM: 5'-nucleotidase, C-terminal domain; Calcineurin-like phosphoesterase; Belongs to the 5'-nucleotidase family. | 0.721 |
| EGN56087.1 | EGN56664.1 | Premu_0611 | Premu_1235 | COGs: COG0572 Uridine kinase; InterPro IPR006083; KEGG: pmz:HMPREF0659_A6356 phosphoribulokinase/uridine kinase family protein; PFAM: Phosphoribulokinase/uridine kinase; SPTR: Phosphoribulokinase family protein; IMG reference gene:2503874638; PFAM: Phosphoribulokinase / Uridine kinase family. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.744 |
| EGN56087.1 | EGN57102.1 | Premu_0611 | Premu_1697 | COGs: COG0572 Uridine kinase; InterPro IPR006083; KEGG: pmz:HMPREF0659_A6356 phosphoribulokinase/uridine kinase family protein; PFAM: Phosphoribulokinase/uridine kinase; SPTR: Phosphoribulokinase family protein; IMG reference gene:2503874638; PFAM: Phosphoribulokinase / Uridine kinase family. | Inosine guanosine and xanthosine phosphorylase family; COGs: COG0005 Purine nucleoside phosphorylase; InterPro IPR011268:IPR000845; KEGG: pmz:HMPREF0659_A5845 purine nucleoside phosphorylase I, inosine and guanosine-specific; PFAM: Nucleoside phosphorylase domain; PRIAM: Purine-nucleoside phosphorylase; SPTR: Purine nucleoside phosphorylase I, inosine and guanosine-specific; TIGRFAM: Inosine guanosine/xanthosine phosphorylase; IMG reference gene:2503875743; PFAM: Phosphorylase superfamily; TIGRFAM: inosine guanosine and xanthosine phosphorylase family. | 0.406 |
| EGN56087.1 | surE | Premu_0611 | Premu_2585 | COGs: COG0572 Uridine kinase; InterPro IPR006083; KEGG: pmz:HMPREF0659_A6356 phosphoribulokinase/uridine kinase family protein; PFAM: Phosphoribulokinase/uridine kinase; SPTR: Phosphoribulokinase family protein; IMG reference gene:2503874638; PFAM: Phosphoribulokinase / Uridine kinase family. | 5'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.756 |
| EGN56087.1 | udk | Premu_0611 | Premu_2148 | COGs: COG0572 Uridine kinase; InterPro IPR006083; KEGG: pmz:HMPREF0659_A6356 phosphoribulokinase/uridine kinase family protein; PFAM: Phosphoribulokinase/uridine kinase; SPTR: Phosphoribulokinase family protein; IMG reference gene:2503874638; PFAM: Phosphoribulokinase / Uridine kinase family. | COGs: COG0572 Uridine kinase; HAMAP: Uridine kinase; InterPro IPR006083:IPR000764:IPR003593; KEGG: pmz:HMPREF0659_A7128 uridine kinase; PFAM: Phosphoribulokinase/uridine kinase; SMART: ATPase, AAA+ type, core; SPTR: Uridine kinase; TIGRFAM: Uridine kinase; IMG reference gene:2503876208; PFAM: Phosphoribulokinase / Uridine kinase family; TIGRFAM: uridine kinase. | 0.713 |
| EGN56656.1 | EGN55627.1 | Premu_1227 | Premu_0136 | NAD(+) diphosphatase; COGs: COG2816 NTP pyrophosphohydrolase containing a Zn-finger probably nucleic-acid-binding; InterPro IPR015375:IPR015376:IPR000086; KEGG: pmz:HMPREF0659_A5588 hydrolase, NUDIX family; PFAM: NUDIX hydrolase domain; Zinc ribbon, NADH pyrophosphatase; NADH pyrophosphatase-like, N-terminal; PRIAM: NAD(+) diphosphatase; SPTR: NAD(+) diphosphatase; IMG reference gene:2503875268; PFAM: NADH pyrophosphatase zinc ribbon domain; NUDIX domain. | COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR004843; KEGG: pmz:HMPREF0659_A5395 Ser/Thr phosphatase family protein; PFAM: Metallo-dependent phosphatase; PRIAM: 5'-nucleotidase; SPTR: Putative uncharacterized protein; IMG reference gene:2503874142; PFAM: Calcineurin-like phosphoesterase. | 0.732 |
| EGN56656.1 | EGN56657.1 | Premu_1227 | Premu_1228 | NAD(+) diphosphatase; COGs: COG2816 NTP pyrophosphohydrolase containing a Zn-finger probably nucleic-acid-binding; InterPro IPR015375:IPR015376:IPR000086; KEGG: pmz:HMPREF0659_A5588 hydrolase, NUDIX family; PFAM: NUDIX hydrolase domain; Zinc ribbon, NADH pyrophosphatase; NADH pyrophosphatase-like, N-terminal; PRIAM: NAD(+) diphosphatase; SPTR: NAD(+) diphosphatase; IMG reference gene:2503875268; PFAM: NADH pyrophosphatase zinc ribbon domain; NUDIX domain. | 2',3'-cyclic-nucleotide 2'-phosphodiesterase; COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR004843:IPR008334; KEGG: pmz:HMPREF0659_A5589 5'-nucleotidase, C-terminal domain protein; PFAM: Metallo-dependent phosphatase; 5'-Nucleotidase, C-terminal; PRIAM: 2',3'-cyclic-nucleotide 2'-phosphodiesterase; SPTR: 5'-nucleotidase; IMG reference gene:2503875269; PFAM: 5'-nucleotidase, C-terminal domain; Calcineurin-like phosphoesterase; Belongs to the 5'-nucleotidase family. | 0.923 |