STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EGN56666.1Forkhead-associated protein; InterPro IPR000253; KEGG: pru:PRU_1315 FHA domain-containing protein; PFAM: Forkhead-associated (FHA) domain; SPTR: FHA domain protein; IMG reference gene:2503875278; PFAM: FHA domain. (178 aa)    
Predicted Functional Partners:
EGN58153.1
Histidine kinase; COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterPro IPR003594; KEGG: pmz:HMPREF0659_A7241 ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; PFAM: ATPase-like, ATP-binding domain; SMART: ATPase-like, ATP-binding domain; SPTR: Putative uncharacterized protein; IMG reference gene:2503876886; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
  
 0.875
EGN56665.1
Transcriptional regulator, AraC family; COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR018060:IPR000005; KEGG: pmz:HMPREF0659_A5507 transcriptional regulator, AraC family; PFAM: HTH transcriptional regulator, AraC; SMART: Helix-turn-helix, AraC type, DNA binding domain; SPTR: Transcriptional regulator, AraC family; IMG reference gene:2503875277; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family.
       0.773
EGN56263.1
InterPro IPR005543; KEGG: pmz:HMPREF0659_A6207 PASTA domain protein; PFAM: PASTA; SMART: PASTA; SPTR: Putative uncharacterized protein; IMG reference gene:2503874833; PFAM: PASTA domain.
   
 
 0.754
EGN56667.1
Sporulation domain-containing protein; InterPro IPR007730; KEGG: pru:PRU_1314 hypothetical protein; PFAM: Sporulation-related domain; SPTR: Putative uncharacterized protein; IMG reference gene:2503875279; PFAM: Sporulation related domain.
       0.754
EGN58131.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
    
 
 0.682
ribBA
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
 0.633
EGN57551.1
COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR002078:IPR002197:IPR003593; KEGG: pmz:HMPREF0659_A5948 sigma-54 interaction domain protein; PFAM: RNA polymerase sigma factor 54, interaction; Helix-turn-helix, Fis-type; SMART: ATPase, AAA+ type, core; SPTR: Sigma-54-dependent transcriptional regulator; IMG reference gene:2503876221; PFAM: Bacterial regulatory protein, Fis family; Sigma-54 interaction domain.
    
 0.622
EGN56668.1
dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
       0.608
EGN55791.1
Transcriptional regulator, AraC family; COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR011110:IPR011123:IPR000005:IPR018060; KEGG: pru:PRU_2668 AraC family transcriptional regulator; PFAM: Two component regulator three Y; Two component regulator propeller; HTH transcriptional regulator, AraC; SMART: Helix-turn-helix, AraC type, DNA binding domain; SPTR: Two-component system sensor histidine kinase/response regulator; IMG reference gene:2503874321; PFAM: Y_Y_Y domain; Two component regulator propeller; Bacterial regulatory helix-turn-helix proteins, AraC family.
  
 
 0.601
EGN56361.1
Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR011110:IPR011123:IPR003661:IPR003594:IPR 001789:IPR000005:IPR018060; KEGG: pru:PRU_0278 sensor histidine kinase/DNA-binding response regulator; PFAM: ATPase-like, ATP-binding domain; Two component regulator three Y; Two component regulator propeller; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Signal transduction response regulator, receiver domain; HTH transcriptional regulator, AraC; SMART: Signal transduction response regulator, receiver domain; ATPase-like, AT [...]
  
 
 0.601
Your Current Organism:
Prevotella multisaccharivorax
NCBI taxonomy Id: 688246
Other names: P. multisaccharivorax DSM 17128, Prevotella multisaccharivorax DSM 17128, Prevotella multisaccharivorax JCM 12954, Prevotella multisaccharivorax str. DSM 17128, Prevotella multisaccharivorax strain DSM 17128
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