STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EGN56816.1KEGG: lcr:LCRIS_00477 biotin carboxylase; SPTR: Putative uncharacterized protein; IMG reference gene:2503875432; PFAM: Protein of unknown function (DUF2791). (445 aa)    
Predicted Functional Partners:
EGN56817.1
KEGG: lga:LGAS_1558 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503875433.
 
     0.950
EGN56812.1
DEAD/DEAH box helicase domain protein; COGs: COG1201 Lhr-like helicase; InterPro IPR014001:IPR001650:IPR011545; KEGG: ljo:LJ1760 hypothetical protein; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; Helicase, C-terminal; SPTR: DEAD/DEAH box helicase domain protein; IMG reference gene:2503875427; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase.
 
     0.790
EGN56818.1
KEGG: pru:PRU_0080 hypothetical protein; SPTR: Putative lipoprotein; IMG reference gene:2503875434; PFAM: X-Pro dipeptidyl-peptidase (S15 family).
       0.773
EGN55679.1
COGs: COG0685 5 10-methylenetetrahydrofolate reductase; InterPro IPR003171; KEGG: pru:PRU_1700 methylenetetrahydrofolate reductase (NAD(P)H); PFAM: Methylenetetrahydrofolate reductase; PRIAM: Methylenetetrahydrofolate reductase (NAD(P)H); SPTR: Methylenetetrahydrofolate reductase; IMG reference gene:2503874199; PFAM: Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
   
 
 0.731
EGN58134.1
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
   
 
 0.720
EGN58172.1
COGs: COG1410 Methionine synthase I cobalamin-binding domain; InterPro IPR004223; KEGG: pmz:HMPREF0659_A6000 vitamin B12 dependent methionine synthase, activation domain protein; PFAM: Vitamin B12-dependent methionine synthase, activation domain; PRIAM: Methionine synthase; SPTR: 5-methyltetrahydrofolate--homocysteine methyltransferase; IMG reference gene:2503876906; PFAM: Vitamin B12 dependent methionine synthase, activation domain.
   
 
 0.720
EGN56832.1
COGs: COG0527 Aspartokinase; InterProIPR001341:IPR001048:IPR002912:IPR005106:IPR 001342; KEGG: pru:PRU_1016 aspartate kinase/homoserine dehydrogenase; PFAM: Homoserine dehydrogenase, catalytic; Aspartate/glutamate/uridylate kinase; Amino acid-binding ACT; Aspartate/homoserine dehydrogenase, NAD-binding; SPTR: Aspartokinase/homoserine dehydrogenase; TIGRFAM: Aspartate kinase domain; IMG reference gene:2503875449; PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; Amino acid kinase family; TIGRFAM: aspartate kinase.
  
 
 0.607
metAA
Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.
  
    0.583
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
  
 0.553
metE
Methionine synthase (B12-independent); Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
  
 
 0.541
Your Current Organism:
Prevotella multisaccharivorax
NCBI taxonomy Id: 688246
Other names: P. multisaccharivorax DSM 17128, Prevotella multisaccharivorax DSM 17128, Prevotella multisaccharivorax JCM 12954, Prevotella multisaccharivorax str. DSM 17128, Prevotella multisaccharivorax strain DSM 17128
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