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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EGN57379.1KpsF/GutQ family protein; COGs: COG0794 sugar phosphate isomerase involved in capsule formation; InterPro IPR001347:IPR000644:IPR004800; KEGG: pmz:HMPREF0659_A5655 putative arabinose 5-phosphate isomerase; PFAM: Sugar isomerase (SIS); Cystathionine beta-synthase, core; PRIAM: Arabinose-5-phosphate isomerase; SPTR: Arabinose 5-phosphate isomerase; TIGRFAM: KpsF/GutQ; IMG reference gene:2503876039; PFAM: CBS domain; SIS domain; TIGRFAM: KpsF/GutQ family protein; Belongs to the SIS family. GutQ/KpsF subfamily. (327 aa)    
Predicted Functional Partners:
EGN57377.1
2-dehydro-3-deoxyphosphooctonate aldolase; COGs: COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; InterPro IPR006218:IPR006269; KEGG: pmz:HMPREF0659_A5656 3-deoxy-8-phosphooctulonate synthase; PFAM: DAHP synthetase I/KDSA; PRIAM: 3-deoxy-8-phosphooctulonate synthase; SPTR: 3-deoxy-8-phosphooctulonate synthase; TIGRFAM: 3-deoxy-8-phosphooctulonate synthase; IMG reference gene:2503876037; PFAM: DAHP synthetase I family; TIGRFAM: 3-deoxy-8-phosphooctulonate synthase; Belongs to the KdsA family.
 
 
 0.993
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
 0.918
EGN55578.1
3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; COGs: COG1778 Low specificity phosphatase (HAD superfamily); InterPro IPR010023; KEGG: pmz:HMPREF0659_A6733 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; SPTR: YrbI family phosphatase; TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; IMG reference gene:2503874086; TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family.
 
 
 0.887
kdsB
3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
 
   
 0.875
EGN57380.1
Phospholipase D/Transphosphatidylase; COGs: COG1502 Phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase; InterPro IPR001736; KEGG: pmz:HMPREF0659_A5654 phospholipase D domain protein; PFAM: Phospholipase D/Transphosphatidylase; SMART: Phospholipase D/Transphosphatidylase; SPTR: Cardiolipin synthetase; IMG reference gene:2503876040; PFAM: Phospholipase D Active site motif.
    
 0.870
lpxK
lipid-A-disaccharide kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
 
   
 0.855
EGN55639.1
Three-deoxy-D-manno-octulosonic-acid transferase domain-containing protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.
 
   
 0.829
EGN56526.1
acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
 
 
 0.807
lpxD
UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
 
  
 0.793
EGN57155.1
acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; COGs: COG1043 Acyl-(acyl carrier protein); InterPro IPR001451; KEGG: pru:PRU_1846 putative acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase; PFAM: Bacterial transferase hexapeptide repeat; PRIAM:Acyl-[acyl-carrier-protein]--UDP-N-acetylgluc osamineO-acyltransferase; SPTR:Acyl-(Acyl-carrier-protein)-UDP-N-acetylglucos amineO-acyltransferase; IMG reference gene:2503875796; PFAM: Bacterial transferase hexapeptide (three repeats); TIGRFAM: acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-ac [...]
 
 
 0.790
Your Current Organism:
Prevotella multisaccharivorax
NCBI taxonomy Id: 688246
Other names: P. multisaccharivorax DSM 17128, Prevotella multisaccharivorax DSM 17128, Prevotella multisaccharivorax JCM 12954, Prevotella multisaccharivorax str. DSM 17128, Prevotella multisaccharivorax strain DSM 17128
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