| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EGN55599.1 | EGN57409.1 | Premu_0106 | Premu_2011 | Hypothetical protein; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase H family. | KEGG: pmz:HMPREF0659_A6745 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503876069. | 0.572 |
| EGN55615.1 | EGN55932.1 | Premu_0123 | Premu_0450 | Haloacid dehalogenase domain protein hydrolase; COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR005834; KEGG: pmz:HMPREF0659_A5635 haloacid dehalogenase-like hydrolase; PFAM: Haloacid dehalogenase-like hydrolase; SPTR: Haloacid dehalogenase-like hydrolase; IMG reference gene:2503874129; PFAM: haloacid dehalogenase-like hydrolase. | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | 0.464 |
| EGN55615.1 | EGN57073.1 | Premu_0123 | Premu_1667 | Haloacid dehalogenase domain protein hydrolase; COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR005834; KEGG: pmz:HMPREF0659_A5635 haloacid dehalogenase-like hydrolase; PFAM: Haloacid dehalogenase-like hydrolase; SPTR: Haloacid dehalogenase-like hydrolase; IMG reference gene:2503874129; PFAM: haloacid dehalogenase-like hydrolase. | CinA domain protein; COGs: COG1546 Uncharacterized protein (competence- and mitomycin-induced); InterPro IPR008136; KEGG: pmz:HMPREF0659_A6780 competence/damage-inducible protein CinA C-terminal domain protein; PFAM: CinA, C-terminal; SPTR: Competence/damage-inducible protein CinA; TIGRFAM: CinA, C-terminal; IMG reference gene:2503875713; PFAM: Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA C-terminal domain; Belongs to the CinA family. | 0.752 |
| EGN55615.1 | EGN57409.1 | Premu_0123 | Premu_2011 | Haloacid dehalogenase domain protein hydrolase; COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR005834; KEGG: pmz:HMPREF0659_A5635 haloacid dehalogenase-like hydrolase; PFAM: Haloacid dehalogenase-like hydrolase; SPTR: Haloacid dehalogenase-like hydrolase; IMG reference gene:2503874129; PFAM: haloacid dehalogenase-like hydrolase. | KEGG: pmz:HMPREF0659_A6745 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503876069. | 0.524 |
| EGN55615.1 | nadE | Premu_0123 | Premu_2649 | Haloacid dehalogenase domain protein hydrolase; COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR005834; KEGG: pmz:HMPREF0659_A5635 haloacid dehalogenase-like hydrolase; PFAM: Haloacid dehalogenase-like hydrolase; SPTR: Haloacid dehalogenase-like hydrolase; IMG reference gene:2503874129; PFAM: haloacid dehalogenase-like hydrolase. | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.460 |
| EGN55932.1 | EGN55615.1 | Premu_0450 | Premu_0123 | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | Haloacid dehalogenase domain protein hydrolase; COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR005834; KEGG: pmz:HMPREF0659_A5635 haloacid dehalogenase-like hydrolase; PFAM: Haloacid dehalogenase-like hydrolase; SPTR: Haloacid dehalogenase-like hydrolase; IMG reference gene:2503874129; PFAM: haloacid dehalogenase-like hydrolase. | 0.464 |
| EGN55932.1 | EGN56138.1 | Premu_0450 | Premu_0665 | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | COGs: COG0846 NAD-dependent protein deacetylase SIR2 family; HAMAP: NAD-dependent histone deacetylase, silent information regulator Sir2; InterPro IPR003000; KEGG: pru:PRU_2859 NAD-dependent deacetylase; PFAM: NAD-dependent histone deacetylase, silent information regulator Sir2; SPTR: NAD-dependent deacetylase; IMG reference gene:2503874694; PFAM: Sir2 family. | 0.572 |
| EGN55932.1 | EGN57073.1 | Premu_0450 | Premu_1667 | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | CinA domain protein; COGs: COG1546 Uncharacterized protein (competence- and mitomycin-induced); InterPro IPR008136; KEGG: pmz:HMPREF0659_A6780 competence/damage-inducible protein CinA C-terminal domain protein; PFAM: CinA, C-terminal; SPTR: Competence/damage-inducible protein CinA; TIGRFAM: CinA, C-terminal; IMG reference gene:2503875713; PFAM: Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA C-terminal domain; Belongs to the CinA family. | 0.927 |
| EGN55932.1 | EGN57409.1 | Premu_0450 | Premu_2011 | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | KEGG: pmz:HMPREF0659_A6745 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503876069. | 0.540 |
| EGN55932.1 | nadE | Premu_0450 | Premu_2649 | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.722 |
| EGN56138.1 | EGN55932.1 | Premu_0665 | Premu_0450 | COGs: COG0846 NAD-dependent protein deacetylase SIR2 family; HAMAP: NAD-dependent histone deacetylase, silent information regulator Sir2; InterPro IPR003000; KEGG: pru:PRU_2859 NAD-dependent deacetylase; PFAM: NAD-dependent histone deacetylase, silent information regulator Sir2; SPTR: NAD-dependent deacetylase; IMG reference gene:2503874694; PFAM: Sir2 family. | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | 0.572 |
| EGN56138.1 | EGN57073.1 | Premu_0665 | Premu_1667 | COGs: COG0846 NAD-dependent protein deacetylase SIR2 family; HAMAP: NAD-dependent histone deacetylase, silent information regulator Sir2; InterPro IPR003000; KEGG: pru:PRU_2859 NAD-dependent deacetylase; PFAM: NAD-dependent histone deacetylase, silent information regulator Sir2; SPTR: NAD-dependent deacetylase; IMG reference gene:2503874694; PFAM: Sir2 family. | CinA domain protein; COGs: COG1546 Uncharacterized protein (competence- and mitomycin-induced); InterPro IPR008136; KEGG: pmz:HMPREF0659_A6780 competence/damage-inducible protein CinA C-terminal domain protein; PFAM: CinA, C-terminal; SPTR: Competence/damage-inducible protein CinA; TIGRFAM: CinA, C-terminal; IMG reference gene:2503875713; PFAM: Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA C-terminal domain; Belongs to the CinA family. | 0.617 |
| EGN56138.1 | EGN57409.1 | Premu_0665 | Premu_2011 | COGs: COG0846 NAD-dependent protein deacetylase SIR2 family; HAMAP: NAD-dependent histone deacetylase, silent information regulator Sir2; InterPro IPR003000; KEGG: pru:PRU_2859 NAD-dependent deacetylase; PFAM: NAD-dependent histone deacetylase, silent information regulator Sir2; SPTR: NAD-dependent deacetylase; IMG reference gene:2503874694; PFAM: Sir2 family. | KEGG: pmz:HMPREF0659_A6745 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503876069. | 0.698 |
| EGN56138.1 | nadE | Premu_0665 | Premu_2649 | COGs: COG0846 NAD-dependent protein deacetylase SIR2 family; HAMAP: NAD-dependent histone deacetylase, silent information regulator Sir2; InterPro IPR003000; KEGG: pru:PRU_2859 NAD-dependent deacetylase; PFAM: NAD-dependent histone deacetylase, silent information regulator Sir2; SPTR: NAD-dependent deacetylase; IMG reference gene:2503874694; PFAM: Sir2 family. | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.923 |
| EGN56229.1 | EGN57409.1 | Premu_0768 | Premu_2011 | Putative ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase H family. | KEGG: pmz:HMPREF0659_A6745 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503876069. | 0.576 |
| EGN56756.1 | EGN57409.1 | Premu_1327 | Premu_2011 | Protein of unknown function DUF1460; InterPro IPR010846; KEGG: pru:PRU_0459 hypothetical protein; PFAM: Protein of unknown function DUF1460; SPTR: Putative uncharacterized protein; IMG reference gene:2503875369; PFAM: Protein of unknown function (DUF1460). | KEGG: pmz:HMPREF0659_A6745 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503876069. | 0.805 |
| EGN57073.1 | EGN55615.1 | Premu_1667 | Premu_0123 | CinA domain protein; COGs: COG1546 Uncharacterized protein (competence- and mitomycin-induced); InterPro IPR008136; KEGG: pmz:HMPREF0659_A6780 competence/damage-inducible protein CinA C-terminal domain protein; PFAM: CinA, C-terminal; SPTR: Competence/damage-inducible protein CinA; TIGRFAM: CinA, C-terminal; IMG reference gene:2503875713; PFAM: Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA C-terminal domain; Belongs to the CinA family. | Haloacid dehalogenase domain protein hydrolase; COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR005834; KEGG: pmz:HMPREF0659_A5635 haloacid dehalogenase-like hydrolase; PFAM: Haloacid dehalogenase-like hydrolase; SPTR: Haloacid dehalogenase-like hydrolase; IMG reference gene:2503874129; PFAM: haloacid dehalogenase-like hydrolase. | 0.752 |
| EGN57073.1 | EGN55932.1 | Premu_1667 | Premu_0450 | CinA domain protein; COGs: COG1546 Uncharacterized protein (competence- and mitomycin-induced); InterPro IPR008136; KEGG: pmz:HMPREF0659_A6780 competence/damage-inducible protein CinA C-terminal domain protein; PFAM: CinA, C-terminal; SPTR: Competence/damage-inducible protein CinA; TIGRFAM: CinA, C-terminal; IMG reference gene:2503875713; PFAM: Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA C-terminal domain; Belongs to the CinA family. | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | 0.927 |
| EGN57073.1 | EGN56138.1 | Premu_1667 | Premu_0665 | CinA domain protein; COGs: COG1546 Uncharacterized protein (competence- and mitomycin-induced); InterPro IPR008136; KEGG: pmz:HMPREF0659_A6780 competence/damage-inducible protein CinA C-terminal domain protein; PFAM: CinA, C-terminal; SPTR: Competence/damage-inducible protein CinA; TIGRFAM: CinA, C-terminal; IMG reference gene:2503875713; PFAM: Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA C-terminal domain; Belongs to the CinA family. | COGs: COG0846 NAD-dependent protein deacetylase SIR2 family; HAMAP: NAD-dependent histone deacetylase, silent information regulator Sir2; InterPro IPR003000; KEGG: pru:PRU_2859 NAD-dependent deacetylase; PFAM: NAD-dependent histone deacetylase, silent information regulator Sir2; SPTR: NAD-dependent deacetylase; IMG reference gene:2503874694; PFAM: Sir2 family. | 0.617 |
| EGN57073.1 | EGN57409.1 | Premu_1667 | Premu_2011 | CinA domain protein; COGs: COG1546 Uncharacterized protein (competence- and mitomycin-induced); InterPro IPR008136; KEGG: pmz:HMPREF0659_A6780 competence/damage-inducible protein CinA C-terminal domain protein; PFAM: CinA, C-terminal; SPTR: Competence/damage-inducible protein CinA; TIGRFAM: CinA, C-terminal; IMG reference gene:2503875713; PFAM: Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA C-terminal domain; Belongs to the CinA family. | KEGG: pmz:HMPREF0659_A6745 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503876069. | 0.708 |