Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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EGN57416.1InterPro IPR011742:IPR013383; KEGG: mvu:Metvu_1220 CRISPR-associated protein, TM1812 family; PFAM: CRISPR-associated protein, TM1812; SPTR: CRISPR-associated dxthg domain-containing protein; TIGRFAM: CRISPR-associated protein, TM1812; CRISPR-associated protein DxTHG, conserved site; IMG reference gene:2503876077; PFAM: CRISPR-associated protein (cas_TM1812); TIGRFAM: CRISPR-associated protein, TM1812 family; CRISPR-associated DxTHG motif protein. (561 aa)    
Predicted Functional Partners:
EGN57415.1
Hypothetical protein; KEGG: dre:566238 zgc:165453; SPTR: Putative uncharacterized protein; IMG reference gene:2503876076.
       0.779
cas1
CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
   
 0.728
EGN57417.1
Hypothetical protein; KEGG: pla:Plav_3509 exonuclease V subunit alpha; SPTR: Helicase; IMG reference gene:2503876078; PFAM: Protein of unknown function (DUF815).
       0.676
EGN56161.1
KEGG: fsu:Fisuc_1557 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503874720.
 
   
 0.643
EGN56167.1
InterPro IPR015093; KEGG: tye:THEYE_A0066 hypothetical protein; PFAM: Protein of unknown function DUF1887; SPTR: Putative uncharacterized protein; IMG reference gene:2503874726; PFAM: Domain of unknown function (DUF1887).
 
   
 0.607
cas2
CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
   
 0.593
EGN56164.1
Protein of unknown function DUF324; COGs: COG1337 Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily); InterPro IPR005537; KEGG: fsu:Fisuc_1560 protein of unknown function DUF324; PFAM: Protein of unknown function DUF324; SPTR: CRISPR-associated RAMP protein; IMG reference gene:2503874723; PFAM: RAMP superfamily.
 
     0.562
EGN57419.1
VirE protein; InterPro IPR014907; KEGG: pdi:BDI_0295 hypothetical protein; PFAM: VirE N-terminal; SPTR: VirE N-domain protein; IMG reference gene:2503876080; PFAM: VirE N-terminal domain.
 
     0.541
cas1-2
CRISPR-associated protein, Cas1 family; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
   
 0.496
EGN56162.1
Protein of unknown function DUF324; InterPro IPR005537; KEGG: vvy:VVA1540 hypothetical protein; PFAM: Protein of unknown function DUF324; SPTR: CRISPR-associated RAMP protein; IMG reference gene:2503874721; PFAM: RAMP superfamily.
 
     0.486
Your Current Organism:
Prevotella multisaccharivorax
NCBI taxonomy Id: 688246
Other names: P. multisaccharivorax DSM 17128, Prevotella multisaccharivorax DSM 17128, Prevotella multisaccharivorax JCM 12954, Prevotella multisaccharivorax str. DSM 17128, Prevotella multisaccharivorax strain DSM 17128
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