Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EGN57417.1Hypothetical protein; KEGG: pla:Plav_3509 exonuclease V subunit alpha; SPTR: Helicase; IMG reference gene:2503876078; PFAM: Protein of unknown function (DUF815). (161 aa)    
Predicted Functional Partners:
EGN57416.1
InterPro IPR011742:IPR013383; KEGG: mvu:Metvu_1220 CRISPR-associated protein, TM1812 family; PFAM: CRISPR-associated protein, TM1812; SPTR: CRISPR-associated dxthg domain-containing protein; TIGRFAM: CRISPR-associated protein, TM1812; CRISPR-associated protein DxTHG, conserved site; IMG reference gene:2503876077; PFAM: CRISPR-associated protein (cas_TM1812); TIGRFAM: CRISPR-associated protein, TM1812 family; CRISPR-associated DxTHG motif protein.
       0.676
EGN57415.1
Hypothetical protein; KEGG: dre:566238 zgc:165453; SPTR: Putative uncharacterized protein; IMG reference gene:2503876076.
       0.675
cas1
CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
       0.472
EGN57419.1
VirE protein; InterPro IPR014907; KEGG: pdi:BDI_0295 hypothetical protein; PFAM: VirE N-terminal; SPTR: VirE N-domain protein; IMG reference gene:2503876080; PFAM: VirE N-terminal domain.
       0.458
EGN56986.1
UvrD/REP helicase; COGs: COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains); InterPro IPR000212; KEGG: pru:PRU_1649 UvrD/REP family ATP-dependent DNA helicase; PFAM: DNA helicase, UvrD/REP type; SPTR: Putative uncharacterized protein; IMG reference gene:2503875619; PFAM: Domain of unknown function DUF83; UvrD/REP helicase; Belongs to the helicase family. UvrD subfamily.
 
 
 0.456
purL
Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
  
    0.450
EGN57616.1
KEGG: pru:PRU_2225 putative TonB dependent receptor; SPTR: Putative outer membrane protein probably involved in nutrient binding; IMG reference gene:2503876294.
  
     0.449
cas2
CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
       0.444
EGN58131.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 0.422
msrA
Peptide methionine sulfoxide reductase msrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
     
 0.418
Your Current Organism:
Prevotella multisaccharivorax
NCBI taxonomy Id: 688246
Other names: P. multisaccharivorax DSM 17128, Prevotella multisaccharivorax DSM 17128, Prevotella multisaccharivorax JCM 12954, Prevotella multisaccharivorax str. DSM 17128, Prevotella multisaccharivorax strain DSM 17128
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