Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EGN57543.1Short-chain dehydrogenase/reductase SDR; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198:IPR020842; KEGG: cat:CA2559_03910 probable 3-oxoacyl-(acyl-carrier protein) reductase; PFAM: Short-chain dehydrogenase/reductase SDR; SMART: Polyketide synthase/Fatty acid synthase, KR; SPTR: 3-oxoacyl-[acyl-carrier-protein] reductase; IMG reference gene:2503876213; PFAM: short chain dehydrogenase. (243 aa)    
Predicted Functional Partners:
EGN57390.1
COGs: COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; InterPro IPR014030:IPR014031:IPR020841; KEGG: dfe:Dfer_1997 beta-ketoacyl synthase; PFAM: Beta-ketoacyl synthase, C-terminal; Beta-ketoacyl synthase, N-terminal; PRIAM: Beta-ketoacyl-acyl-carrier-protein synthase I; SMART: Polyketide synthase, beta-ketoacyl synthase domain; SPTR: Beta-ketoacyl-acyl-carrier-protein synthase I; IMG reference gene:2503876050; PFAM: Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
 0.953
EGN58215.1
Beta-ketoacyl synthase; COGs: COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; InterPro IPR020841:IPR014030:IPR014031; KEGG: cpi:Cpin_1861 beta-ketoacyl synthase; PFAM: Beta-ketoacyl synthase, C-terminal; Beta-ketoacyl synthase, N-terminal; SMART: Polyketide synthase, beta-ketoacyl synthase domain; SPTR: 3-oxoacyl-[acyl-carrier-protein] synthase II; IMG reference gene:2503876950; PFAM: Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
 0.922
EGN56587.1
COGs: COG0331 (acyl-carrier-protein) S-malonyltransferase; InterPro IPR004410:IPR020801:IPR014043; KEGG: pmz:HMPREF0659_A6909 [acyl-carrier-protein] S-malonyltransferase; PFAM: Acyl transferase; PRIAM: [Acyl-carrier-protein] S-malonyltransferase; SMART: Polyketide synthase, acyl transferase domain; SPTR: Malonyl CoA-acyl carrier protein transacylase; TIGRFAM: Malonyl CoA-acyl carrier protein transacylase; IMG reference gene:2503875191; PFAM: Acyl transferase domain; TIGRFAM: malonyl CoA-acyl carrier protein transacylase.
 0.920
EGN58255.1
Beta-ketoacyl synthase; COGs: COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; InterPro IPR014030:IPR014031; KEGG: cpi:Cpin_1861 beta-ketoacyl synthase; PFAM: Beta-ketoacyl synthase, C-terminal; Beta-ketoacyl synthase, N-terminal; SPTR: 3-oxoacyl-(Acyl-carrier-protein) synthase II; IMG reference gene:2503874056; PFAM: Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
 0.919
EGN58213.1
COGs: COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; InterPro IPR020841:IPR014030:IPR014031; KEGG: cat:CA2559_03865 3-oxoacyl-(acyl-carrier protein) synthase; PFAM: Beta-ketoacyl synthase, C-terminal; Beta-ketoacyl synthase, N-terminal; PRIAM: Beta-ketoacyl-acyl-carrier-protein synthase I; SMART: Polyketide synthase, beta-ketoacyl synthase domain; SPTR: 3-oxoacyl-[acyl-carrier-protein] synthase II; IMG reference gene:2503876948; PFAM: Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP syn [...]
 
 0.919
EGN58258.1
Beta-ketoacyl-acyl-carrier-protein synthase II; COGs: COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; InterPro IPR014030:IPR014031:IPR020841; KEGG: dfe:Dfer_1989 beta-ketoacyl synthase; PFAM: Beta-ketoacyl synthase, C-terminal; Beta-ketoacyl synthase, N-terminal; PRIAM: Beta-ketoacyl-acyl-carrier-protein synthase II; SMART: Polyketide synthase, beta-ketoacyl synthase domain; SPTR: 3-oxoacyl-[acyl-carrier-protein] synthase II; IMG reference gene:2503874059; PFAM: Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain; Belongs to the thiolase-like superfa [...]
 
 0.915
EGN56123.1
3-oxoacyl-(acyl-carrier-protein) synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
 0.912
EGN56623.1
COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895:IPR019456:IPR002880:IPR019752:IPR 001450:IPR011766; KEGG: pmz:HMPREF0659_A5561 pyruvate synthase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; 4Fe-4S binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: Pyruvate dehydrogenase (NADP(+)); SMART: Pyruvate-flavodoxin oxidoreductase, EKR domain; SPTR: Pyruvate-fla [...]
   
 0.893
EGN57373.1
KEGG: fjo:Fjoh_1081 beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ; SPTR: 3-hydroxymyristoyl/3-hydroxydecanoyl-(Acyl carrier protein) dehydratase; IMG reference gene:2503876033; PFAM: FabA-like domain.
 
 
 0.877
fabH
3-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
 
 
 0.855
Your Current Organism:
Prevotella multisaccharivorax
NCBI taxonomy Id: 688246
Other names: P. multisaccharivorax DSM 17128, Prevotella multisaccharivorax DSM 17128, Prevotella multisaccharivorax JCM 12954, Prevotella multisaccharivorax str. DSM 17128, Prevotella multisaccharivorax strain DSM 17128
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.