Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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[Homology]
Score
EGN57590.1Peptidase M23; COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR016047:IPR018392:IPR002482; KEGG: pmz:HMPREF0659_A5138 peptidase, M23 family; PFAM: Peptidase M23; Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding Lysin subgroup; SPTR: M23/M37 family peptidase; IMG reference gene:2503876267; PFAM: Peptidase family M23; LysM domain. (323 aa)    
Predicted Functional Partners:
EGN55770.1
Peptidase M23; COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR016047; KEGG: bth:BT_4391 putative metalloendopeptidase; PFAM: Peptidase M23; SPTR: M23/M37 peptidase domain protein; IMG reference gene:2503874293; PFAM: Peptidase family M23.
 
  
0.769
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
    
 0.752
EGN57154.1
Peptidoglycan glycosyltransferase; COGs: COG5009 Membrane carboxypeptidase/penicillin-binding protein; InterPro IPR001264:IPR001460; KEGG: pmz:HMPREF0659_A5825 transglycosylase; PFAM: Glycosyl transferase, family 51; Penicillin-binding protein, transpeptidase; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Putative penicillin-binding protein 1A; IMG reference gene:2503875795; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase.
 
  
 0.681
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
  0.675
EGN57821.1
OmpA/MotB domain protein; COGs: COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein; InterPro IPR013105:IPR011659:IPR006665; KEGG: pmz:HMPREF0659_A6804 OmpA family protein; PFAM: Outer membrane protein, OmpA/MotB, C-terminal; WD40-like Beta Propeller; Tetratricopeptide TPR2; SPTR: OmpA family protein; IMG reference gene:2503876522; PFAM: WD40-like Beta Propeller Repeat; OmpA family.
 
 0.672
EGN57391.1
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
 
  
 0.670
recG
ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily.
 
  
 0.645
EGN57073.1
CinA domain protein; COGs: COG1546 Uncharacterized protein (competence- and mitomycin-induced); InterPro IPR008136; KEGG: pmz:HMPREF0659_A6780 competence/damage-inducible protein CinA C-terminal domain protein; PFAM: CinA, C-terminal; SPTR: Competence/damage-inducible protein CinA; TIGRFAM: CinA, C-terminal; IMG reference gene:2503875713; PFAM: Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA C-terminal domain; Belongs to the CinA family.
    
  0.633
mtgA
Monofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family.
 
  
 0.612
EGN57839.1
Peptidoglycan glycosyltransferase; COGs: COG5009 Membrane carboxypeptidase/penicillin-binding protein; InterPro IPR001264:IPR001460; KEGG: pru:PRU_0638 penicillin-binding protein 1A; PFAM: Glycosyl transferase, family 51; Penicillin-binding protein, transpeptidase; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Penicillin-binding protein 1A; IMG reference gene:2503876540; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase.
 
   
 0.609
Your Current Organism:
Prevotella multisaccharivorax
NCBI taxonomy Id: 688246
Other names: P. multisaccharivorax DSM 17128, Prevotella multisaccharivorax DSM 17128, Prevotella multisaccharivorax JCM 12954, Prevotella multisaccharivorax str. DSM 17128, Prevotella multisaccharivorax strain DSM 17128
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