| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EGN55770.1 | EGN57073.1 | Premu_0284 | Premu_1667 | Peptidase M23; COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR016047; KEGG: bth:BT_4391 putative metalloendopeptidase; PFAM: Peptidase M23; SPTR: M23/M37 peptidase domain protein; IMG reference gene:2503874293; PFAM: Peptidase family M23. | CinA domain protein; COGs: COG1546 Uncharacterized protein (competence- and mitomycin-induced); InterPro IPR008136; KEGG: pmz:HMPREF0659_A6780 competence/damage-inducible protein CinA C-terminal domain protein; PFAM: CinA, C-terminal; SPTR: Competence/damage-inducible protein CinA; TIGRFAM: CinA, C-terminal; IMG reference gene:2503875713; PFAM: Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA C-terminal domain; Belongs to the CinA family. | 0.633 |
| EGN55770.1 | EGN57154.1 | Premu_0284 | Premu_1749 | Peptidase M23; COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR016047; KEGG: bth:BT_4391 putative metalloendopeptidase; PFAM: Peptidase M23; SPTR: M23/M37 peptidase domain protein; IMG reference gene:2503874293; PFAM: Peptidase family M23. | Peptidoglycan glycosyltransferase; COGs: COG5009 Membrane carboxypeptidase/penicillin-binding protein; InterPro IPR001264:IPR001460; KEGG: pmz:HMPREF0659_A5825 transglycosylase; PFAM: Glycosyl transferase, family 51; Penicillin-binding protein, transpeptidase; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Putative penicillin-binding protein 1A; IMG reference gene:2503875795; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase. | 0.651 |
| EGN55770.1 | EGN57391.1 | Premu_0284 | Premu_1993 | Peptidase M23; COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR016047; KEGG: bth:BT_4391 putative metalloendopeptidase; PFAM: Peptidase M23; SPTR: M23/M37 peptidase domain protein; IMG reference gene:2503874293; PFAM: Peptidase family M23. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.645 |
| EGN55770.1 | EGN57590.1 | Premu_0284 | Premu_2201 | Peptidase M23; COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR016047; KEGG: bth:BT_4391 putative metalloendopeptidase; PFAM: Peptidase M23; SPTR: M23/M37 peptidase domain protein; IMG reference gene:2503874293; PFAM: Peptidase family M23. | Peptidase M23; COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR016047:IPR018392:IPR002482; KEGG: pmz:HMPREF0659_A5138 peptidase, M23 family; PFAM: Peptidase M23; Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding Lysin subgroup; SPTR: M23/M37 family peptidase; IMG reference gene:2503876267; PFAM: Peptidase family M23; LysM domain. | 0.769 |
| EGN55770.1 | EGN57821.1 | Premu_0284 | Premu_2452 | Peptidase M23; COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR016047; KEGG: bth:BT_4391 putative metalloendopeptidase; PFAM: Peptidase M23; SPTR: M23/M37 peptidase domain protein; IMG reference gene:2503874293; PFAM: Peptidase family M23. | OmpA/MotB domain protein; COGs: COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein; InterPro IPR013105:IPR011659:IPR006665; KEGG: pmz:HMPREF0659_A6804 OmpA family protein; PFAM: Outer membrane protein, OmpA/MotB, C-terminal; WD40-like Beta Propeller; Tetratricopeptide TPR2; SPTR: OmpA family protein; IMG reference gene:2503876522; PFAM: WD40-like Beta Propeller Repeat; OmpA family. | 0.617 |
| EGN55770.1 | EGN57839.1 | Premu_0284 | Premu_2470 | Peptidase M23; COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR016047; KEGG: bth:BT_4391 putative metalloendopeptidase; PFAM: Peptidase M23; SPTR: M23/M37 peptidase domain protein; IMG reference gene:2503874293; PFAM: Peptidase family M23. | Peptidoglycan glycosyltransferase; COGs: COG5009 Membrane carboxypeptidase/penicillin-binding protein; InterPro IPR001264:IPR001460; KEGG: pru:PRU_0638 penicillin-binding protein 1A; PFAM: Glycosyl transferase, family 51; Penicillin-binding protein, transpeptidase; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Penicillin-binding protein 1A; IMG reference gene:2503876540; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase. | 0.650 |
| EGN55770.1 | guaA | Premu_0284 | Premu_1070 | Peptidase M23; COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR016047; KEGG: bth:BT_4391 putative metalloendopeptidase; PFAM: Peptidase M23; SPTR: M23/M37 peptidase domain protein; IMG reference gene:2503874293; PFAM: Peptidase family M23. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.752 |
| EGN55770.1 | guaB | Premu_0284 | Premu_0960 | Peptidase M23; COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR016047; KEGG: bth:BT_4391 putative metalloendopeptidase; PFAM: Peptidase M23; SPTR: M23/M37 peptidase domain protein; IMG reference gene:2503874293; PFAM: Peptidase family M23. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.675 |
| EGN55770.1 | mtgA | Premu_0284 | Premu_1570 | Peptidase M23; COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR016047; KEGG: bth:BT_4391 putative metalloendopeptidase; PFAM: Peptidase M23; SPTR: M23/M37 peptidase domain protein; IMG reference gene:2503874293; PFAM: Peptidase family M23. | Monofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family. | 0.634 |
| EGN57073.1 | EGN55770.1 | Premu_1667 | Premu_0284 | CinA domain protein; COGs: COG1546 Uncharacterized protein (competence- and mitomycin-induced); InterPro IPR008136; KEGG: pmz:HMPREF0659_A6780 competence/damage-inducible protein CinA C-terminal domain protein; PFAM: CinA, C-terminal; SPTR: Competence/damage-inducible protein CinA; TIGRFAM: CinA, C-terminal; IMG reference gene:2503875713; PFAM: Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA C-terminal domain; Belongs to the CinA family. | Peptidase M23; COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR016047; KEGG: bth:BT_4391 putative metalloendopeptidase; PFAM: Peptidase M23; SPTR: M23/M37 peptidase domain protein; IMG reference gene:2503874293; PFAM: Peptidase family M23. | 0.633 |
| EGN57073.1 | EGN57590.1 | Premu_1667 | Premu_2201 | CinA domain protein; COGs: COG1546 Uncharacterized protein (competence- and mitomycin-induced); InterPro IPR008136; KEGG: pmz:HMPREF0659_A6780 competence/damage-inducible protein CinA C-terminal domain protein; PFAM: CinA, C-terminal; SPTR: Competence/damage-inducible protein CinA; TIGRFAM: CinA, C-terminal; IMG reference gene:2503875713; PFAM: Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA C-terminal domain; Belongs to the CinA family. | Peptidase M23; COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR016047:IPR018392:IPR002482; KEGG: pmz:HMPREF0659_A5138 peptidase, M23 family; PFAM: Peptidase M23; Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding Lysin subgroup; SPTR: M23/M37 family peptidase; IMG reference gene:2503876267; PFAM: Peptidase family M23; LysM domain. | 0.633 |
| EGN57154.1 | EGN55770.1 | Premu_1749 | Premu_0284 | Peptidoglycan glycosyltransferase; COGs: COG5009 Membrane carboxypeptidase/penicillin-binding protein; InterPro IPR001264:IPR001460; KEGG: pmz:HMPREF0659_A5825 transglycosylase; PFAM: Glycosyl transferase, family 51; Penicillin-binding protein, transpeptidase; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Putative penicillin-binding protein 1A; IMG reference gene:2503875795; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase. | Peptidase M23; COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR016047; KEGG: bth:BT_4391 putative metalloendopeptidase; PFAM: Peptidase M23; SPTR: M23/M37 peptidase domain protein; IMG reference gene:2503874293; PFAM: Peptidase family M23. | 0.651 |
| EGN57154.1 | EGN57391.1 | Premu_1749 | Premu_1993 | Peptidoglycan glycosyltransferase; COGs: COG5009 Membrane carboxypeptidase/penicillin-binding protein; InterPro IPR001264:IPR001460; KEGG: pmz:HMPREF0659_A5825 transglycosylase; PFAM: Glycosyl transferase, family 51; Penicillin-binding protein, transpeptidase; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Putative penicillin-binding protein 1A; IMG reference gene:2503875795; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.424 |
| EGN57154.1 | EGN57590.1 | Premu_1749 | Premu_2201 | Peptidoglycan glycosyltransferase; COGs: COG5009 Membrane carboxypeptidase/penicillin-binding protein; InterPro IPR001264:IPR001460; KEGG: pmz:HMPREF0659_A5825 transglycosylase; PFAM: Glycosyl transferase, family 51; Penicillin-binding protein, transpeptidase; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Putative penicillin-binding protein 1A; IMG reference gene:2503875795; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase. | Peptidase M23; COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR016047:IPR018392:IPR002482; KEGG: pmz:HMPREF0659_A5138 peptidase, M23 family; PFAM: Peptidase M23; Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding Lysin subgroup; SPTR: M23/M37 family peptidase; IMG reference gene:2503876267; PFAM: Peptidase family M23; LysM domain. | 0.681 |
| EGN57154.1 | EGN57821.1 | Premu_1749 | Premu_2452 | Peptidoglycan glycosyltransferase; COGs: COG5009 Membrane carboxypeptidase/penicillin-binding protein; InterPro IPR001264:IPR001460; KEGG: pmz:HMPREF0659_A5825 transglycosylase; PFAM: Glycosyl transferase, family 51; Penicillin-binding protein, transpeptidase; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Putative penicillin-binding protein 1A; IMG reference gene:2503875795; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase. | OmpA/MotB domain protein; COGs: COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein; InterPro IPR013105:IPR011659:IPR006665; KEGG: pmz:HMPREF0659_A6804 OmpA family protein; PFAM: Outer membrane protein, OmpA/MotB, C-terminal; WD40-like Beta Propeller; Tetratricopeptide TPR2; SPTR: OmpA family protein; IMG reference gene:2503876522; PFAM: WD40-like Beta Propeller Repeat; OmpA family. | 0.476 |
| EGN57154.1 | EGN57839.1 | Premu_1749 | Premu_2470 | Peptidoglycan glycosyltransferase; COGs: COG5009 Membrane carboxypeptidase/penicillin-binding protein; InterPro IPR001264:IPR001460; KEGG: pmz:HMPREF0659_A5825 transglycosylase; PFAM: Glycosyl transferase, family 51; Penicillin-binding protein, transpeptidase; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Putative penicillin-binding protein 1A; IMG reference gene:2503875795; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase. | Peptidoglycan glycosyltransferase; COGs: COG5009 Membrane carboxypeptidase/penicillin-binding protein; InterPro IPR001264:IPR001460; KEGG: pru:PRU_0638 penicillin-binding protein 1A; PFAM: Glycosyl transferase, family 51; Penicillin-binding protein, transpeptidase; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Penicillin-binding protein 1A; IMG reference gene:2503876540; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase. | 0.815 |
| EGN57154.1 | mtgA | Premu_1749 | Premu_1570 | Peptidoglycan glycosyltransferase; COGs: COG5009 Membrane carboxypeptidase/penicillin-binding protein; InterPro IPR001264:IPR001460; KEGG: pmz:HMPREF0659_A5825 transglycosylase; PFAM: Glycosyl transferase, family 51; Penicillin-binding protein, transpeptidase; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Putative penicillin-binding protein 1A; IMG reference gene:2503875795; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase. | Monofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family. | 0.507 |
| EGN57391.1 | EGN55770.1 | Premu_1993 | Premu_0284 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Peptidase M23; COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR016047; KEGG: bth:BT_4391 putative metalloendopeptidase; PFAM: Peptidase M23; SPTR: M23/M37 peptidase domain protein; IMG reference gene:2503874293; PFAM: Peptidase family M23. | 0.645 |
| EGN57391.1 | EGN57154.1 | Premu_1993 | Premu_1749 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Peptidoglycan glycosyltransferase; COGs: COG5009 Membrane carboxypeptidase/penicillin-binding protein; InterPro IPR001264:IPR001460; KEGG: pmz:HMPREF0659_A5825 transglycosylase; PFAM: Glycosyl transferase, family 51; Penicillin-binding protein, transpeptidase; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Putative penicillin-binding protein 1A; IMG reference gene:2503875795; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase. | 0.424 |
| EGN57391.1 | EGN57590.1 | Premu_1993 | Premu_2201 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Peptidase M23; COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR016047:IPR018392:IPR002482; KEGG: pmz:HMPREF0659_A5138 peptidase, M23 family; PFAM: Peptidase M23; Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding Lysin subgroup; SPTR: M23/M37 family peptidase; IMG reference gene:2503876267; PFAM: Peptidase family M23; LysM domain. | 0.670 |