Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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AEH50252.1COGs: COG3458 Acetyl esterase (deacetylase); InterPro IPR008391; KEGG: csc:Csac_2436 acetyl xylan esterase; PFAM: Acetyl xylan esterase; PRIAM: Cephalosporin-C deacetylase; SPTR: Acetyl xylan esterase; PFAM: Acetyl xylan esterase (AXE1). (321 aa)    
Predicted Functional Partners:
AEH50251.1
Ureidoglycolate lyase; COGs: COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase (catechol pathway); InterPro IPR002529; KEGG: vap:Vapar_6065 5-carboxymethyl-2-hydroxymuconate delta-isomerase; PFAM: fumarylacetoacetate (FAA) hydrolase; PRIAM: Ureidoglycolate lyase; SPTR: YisK; PFAM: Fumarylacetoacetate (FAA) hydrolase family.
       0.689
AEH50258.1
COGs: COG3661 Alpha-glucuronidase; InterPro IPR011100:IPR011099:IPR011395; KEGG: trq:TRQ2_0891 alpha-glucuronidase; PFAM: Glycosyl hydrolase 67 middle domain protein; glycosyl hydrolase 67 C-teriminal domain protein; PRIAM: Alpha-glucuronidase; SPTR: Alpha-glucuronidase; PFAM: Glycosyl hydrolase family 67 C-terminus; Glycosyl hydrolase family 67 middle domain; Glycosyl hydrolase family 67 N-terminus; Belongs to the glycosyl hydrolase 67 family.
 
   
 0.574
AEH51574.1
KEGG: ate:Athe_2558 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Trehalose utilisation.
  
     0.573
AEH50250.1
Glycoside hydrolase family 4; COGs: COG1486 Alpha-galactosidase/6-phospho-beta-glucosidase family 4 of glycosyl hydrolase; InterPro IPR001088:IPR019802; KEGG: tnp:Tnap_0550 glycoside hydrolase family 4; PFAM: glycoside hydrolase family 4; SPTR: Alpha-glucosidase, putative; PFAM: Family 4 glycosyl hydrolase; Family 4 glycosyl hydrolase C-terminal domain.
       0.483
uxuA
D-mannonate dehydratase; Catalyzes the dehydration of D-mannonate.
       0.453
AEH50249.1
COGs: COG0246 Mannitol-1-phosphate/altronate dehydrogenase; InterPro IPR013131:IPR013118; KEGG: tpt:Tpet_0856 mannitol dehydrogenase domain-containing protein; PFAM: Mannitol dehydrogenase domain; Mannitol dehydrogenase rossman domain; SPTR: Mannitol dehydrogenase, C-terminal domain; PFAM: Mannitol dehydrogenase C-terminal domain; Mannitol dehydrogenase Rossmann domain.
       0.453
AEH50253.1
COGs: COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems permease components; InterPro IPR000515; KEGG: tnp:Tnap_0690 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Oligopeptide ABC transporter, permease protein; PFAM: Binding-protein-dependent transport system inner membrane component.
       0.412
AEH50489.1
Extracellular solute-binding protein family 1; COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: tit:Thit_1738 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: Extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein.
 
     0.409
AEH51204.1
Glycoside hydrolase family 43; COGs: COG3507 Beta-xylosidase; InterPro IPR006710; KEGG: tpt:Tpet_0637 glycoside hydrolase family protein; PFAM: glycoside hydrolase family 43; SPTR: Glycoside hydrolase, family 43; PFAM: Glycosyl hydrolases family 43; Belongs to the glycosyl hydrolase 43 family.
 
   
 0.403
AEH50254.1
COGs: COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems permease components; InterPro IPR000515; KEGG: tna:CTN_0635 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component.
       0.402
Your Current Organism:
Pseudothermotoga thermarum
NCBI taxonomy Id: 688269
Other names: P. thermarum DSM 5069, Pseudothermotoga thermarum DSM 5069, Pseudothermotoga thermarum LA3, Pseudothermotoga thermarum str. DSM 5069, Pseudothermotoga thermarum strain DSM 5069, Thermotoga thermarum DSM 5069, Thermotoga thermarum LA3
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