Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
AEH50453.1Protein of unknown function DUF370; InterPro IPR007169; KEGG: tle:Tlet_0548 hypothetical protein; PFAM: protein of unknown function DUF370; SPTR: Putative uncharacterized protein; PFAM: Domain of unknown function (DUF370). (83 aa)    
Predicted Functional Partners:
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
    0.637
AEH50450.1
ABC-2 type transporter; InterPro IPR013525:IPR000412:IPR013526; KEGG: tle:Tlet_0552 ABC-2 type transporter; PFAM: ABC-2 type transporter; SPTR: ABC-2 type transporter; PFAM: ABC-2 type transporter.
  
    0.547
AEH50451.1
ABC-2 type transporter; InterPro IPR013525:IPR000412; KEGG: tle:Tlet_0551 ABC-2 type transporter; PFAM: ABC-2 type transporter; SPTR: ABC-2 type transporter; PFAM: ABC-2 type transporter.
       0.544
AEH50452.1
ABC transporter related protein; COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003439:IPR003593:IPR017871; KEGG: tle:Tlet_0550 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related; PFAM: ABC transporter.
       0.542
AEH50449.1
KEGG: tnp:Tnap_0297 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.528
AEH50447.1
InterPro IPR002934; KEGG: adg:Adeg_0500 DNA polymerase beta domain protein region; PFAM: DNA polymerase beta domain protein region; SPTR: DNA polymerase beta domain protein region; PFAM: Nucleotidyltransferase domain.
       0.511
AEH50448.1
HEPN domain protein; COGs: COG2250 conserved hypothetical protein related to C-terminal domain of eukaryotic chaperone SACSIN; InterPro IPR007842; KEGG: dth:DICTH_0449 HEPN domain, putative; PFAM: HEPN domain protein; SMART: HEPN domain protein; SPTR: Hepn domain, putative; PFAM: HEPN domain.
       0.511
AEH50161.1
YicC-like domain-containing protein; COGs: COG1561 Uncharacterized stress-induced protein; InterPro IPR005229:IPR013527:IPR013551; KEGG: tle:Tlet_1630 hypothetical protein; PFAM: YicC-like domain-containing protein; domain of unknown function DUF1732; SPTR: Putative uncharacterized protein; PFAM: YicC-like family, N-terminal region; Domain of unknown function (DUF1732); TIGRFAM: conserved hypothetical protein TIGR00255.
  
    0.472
Your Current Organism:
Pseudothermotoga thermarum
NCBI taxonomy Id: 688269
Other names: P. thermarum DSM 5069, Pseudothermotoga thermarum DSM 5069, Pseudothermotoga thermarum LA3, Pseudothermotoga thermarum str. DSM 5069, Pseudothermotoga thermarum strain DSM 5069, Thermotoga thermarum DSM 5069, Thermotoga thermarum LA3
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