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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH50461.1Hypothetical protein; InterPro IPR013026; KEGG: tle:Tlet_0541 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Tetratricopeptide repeat. (181 aa)    
Predicted Functional Partners:
AEH50459.1
CoA-substrate-specific enzyme activase; COGs: COG1924 Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain); InterPro IPR002731:IPR018709:IPR008275; KEGG: tle:Tlet_0543 putative CoA-substrate-specific enzyme activase; PFAM: ATPase BadF/BadG/BcrA/BcrD type; Protein of unknown function DUF2229, CoA enzyme activase; SPTR: Putative CoA-substrate-specific enzyme activase; TIGRFAM: CoA-substrate-specific enzyme activase; PFAM: 2-hydroxyglutaryl-CoA dehydratase, D-component; BadF/BadG/BcrA/BcrD ATPase family; CoA enzyme activase uncharacterised domain (DUF2229); TIGRFAM: [...]
       0.834
AEH50458.1
NAD+ synthetase; COGs: COG0171 NAD synthase; InterPro IPR003010:IPR014445:IPR003694; KEGG: tnp:Tnap_1541 NAD+ synthetase; PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; SPTR: NAD+ synthetase; TIGRFAM: NAD+ synthetase; PFAM: NAD synthase; TIGRFAM: NAD+ synthetase.
       0.811
AEH50460.1
Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
       0.789
murB
UDP-N-acetylmuramate dehydrogenase; Cell wall formation.
     
 0.784
AEH50462.1
Uncharacterized protein family UPF0029, Impact, N-terminal protein; COGs: COG1739 conserved hypothetical protein; InterPro IPR001498:IPR020569; KEGG: tle:Tlet_0540 hypothetical protein; PFAM: Uncharacterised protein family UPF0029, Impact, N-terminal; SPTR: Putative uncharacterized protein; PFAM: Uncharacterized protein family UPF0029; TIGRFAM: uncharacterized protein, YigZ family.
       0.782
AEH50464.1
COGs: COG0584 Glycerophosphoryl diester phosphodiesterase; InterPro IPR004129; KEGG: tle:Tlet_0538 glycerophosphoryl diester phosphodiesterase; PFAM: glycerophosphoryl diester phosphodiesterase; SPTR: Glycerophosphoryl diester phosphodiesterase; PFAM: Glycerophosphoryl diester phosphodiesterase family.
       0.781
AEH50466.1
Beta-lactamase domain-containing protein; COGs: COG0491 Zn-dependent hydrolase including glyoxylase; KEGG: tle:Tlet_0536 beta-lactamase domain-containing protein; SPTR: Beta-lactamase domain protein; PFAM: Metallo-beta-lactamase superfamily.
       0.781
AEH50465.1
KEGG: tle:Tlet_0537 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF3242).
       0.775
AEH50456.1
Radical SAM domain protein; COGs: COG1032 Fe-S oxidoreductase; InterPro IPR006158:IPR007197:IPR006638:IPR020612:IPR000385; KEGG: tle:Tlet_0545 radical SAM domain-containing protein; PFAM: Radical SAM domain protein; cobalamin B12-binding domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; PFAM: Radical SAM superfamily; B12 binding domain.
       0.769
AEH50457.1
COGs: COG1466 DNA polymerase III delta subunit; InterPro IPR010372; KEGG: tle:Tlet_0544 DNA polymerase III delta; PFAM: DNA polymerase III delta; SPTR: DNA polymerase III delta; PFAM: DNA polymerase III, delta subunit.
       0.769
Your Current Organism:
Pseudothermotoga thermarum
NCBI taxonomy Id: 688269
Other names: P. thermarum DSM 5069, Pseudothermotoga thermarum DSM 5069, Pseudothermotoga thermarum LA3, Pseudothermotoga thermarum str. DSM 5069, Pseudothermotoga thermarum strain DSM 5069, Thermotoga thermarum DSM 5069, Thermotoga thermarum LA3
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