Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
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gene co-occurrence
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[Homology]
Score
AEH51375.17TM receptor with intracellular metal dependent phosphohydrolase; COGs: COG1480 membrane-associated HD superfamily hydrolase; InterPro IPR006675:IPR003607:IPR011621:IPR006674; KEGG: tle:Tlet_1971 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; metal-dependent phosphohydrolase 7TM intracellular region; SMART: metal-dependent phosphohydrolase HD region; SPTR: Metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: HD domain; 7TM receptor with intracellular HD hydrolase; TIGRFAM: uncharacterized domain HDIG. (478 aa)    
Predicted Functional Partners:
ybeY
Protein of unknown function UPF0054; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
  
  
 0.842
AEH51376.1
PhoH family protein; COGs: COG1702 Phosphate starvation-inducible protein PhoH predicted ATPase; InterPro IPR003714; KEGG: tle:Tlet_1972 PhoH family protein; PFAM: PhoH family protein; SPTR: PhoH family protein; manually curated; PFAM: PhoH-like protein.
     
 0.826
AEH51373.1
COGs: COG4198 conserved hypothetical protein; InterPro IPR008323; KEGG: tle:Tlet_1969 hypothetical protein; PFAM: Uncharacterised conserved protein UCP033563; SPTR: Uncharacterised conserved protein UCP033563; PFAM: Protein of unknown function (DUF1015).
       0.820
AEH51372.1
Peptidase membrane zinc metallopeptidase; COGs: COG2738 Zn-dependent protease; InterPro IPR007395; KEGG: tle:Tlet_1968 peptidase membrane zinc metallopeptidase putative; PFAM: peptidase membrane zinc metallopeptidase; SPTR: Peptidase membrane zinc metallopeptidase putative; PFAM: Putative neutral zinc metallopeptidase.
       0.711
AEH51377.1
Isoamylase; COGs: COG1523 Type II secretory pathway pullulanase PulA and related glycosidase; InterPro IPR011837:IPR006589:IPR004193:IPR006047; KEGG: tle:Tlet_0139 glycogen debranching enzyme GlgX; PFAM: glycoside hydrolase family 13 domain protein; alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; SPTR: Glycogen debranching enzyme GlgX; TIGRFAM: glycogen debranching enzyme GlgX; PFAM: Alpha amylase, catalytic domain; Carbohydrate-binding module 48 (Isoamylase N-terminal domain); TIGRFAM: glycogen debranching enzyme GlgX; Belongs to the glycosyl hydrolase 13 family.
       0.559
AEH51371.1
InterPro IPR000620; KEGG: tle:Tlet_1966 hypothetical protein; PFAM: protein of unknown function DUF6 transmembrane; SPTR: Putative uncharacterized protein; PFAM: EamA-like transporter family.
       0.549
AEH50776.1
Competence/damage-inducible protein cinA; COGs: COG1546 Uncharacterized protein (competence- and mitomycin-induced); InterPro IPR001453:IPR008136:IPR008135; KEGG: tle:Tlet_0632 competence/damage-inducible protein CinA; PFAM: CinA domain protein; molybdopterin binding domain; SPTR: CinA-like protein; TIGRFAM: competence/damage-inducible protein CinA; PFAM: Probable molybdopterin binding domain; Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA N-terminal domain; competence/damage-inducible protein CinA C-terminal domain; molybdenum cofactor synthesis domain.
 
     0.510
AEH51378.1
Radical SAM domain protein; COGs: COG1032 Fe-S oxidoreductase; InterPro IPR006638:IPR013704:IPR007197; KEGG: tna:CTN_0332 radical SAM N-terminal domain protein; PFAM: Radical SAM domain protein; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: UPF0313 protein CTN_0332; PFAM: Radical SAM superfamily; Radical SAM N-terminal.
  
    0.504
Your Current Organism:
Pseudothermotoga thermarum
NCBI taxonomy Id: 688269
Other names: P. thermarum DSM 5069, Pseudothermotoga thermarum DSM 5069, Pseudothermotoga thermarum LA3, Pseudothermotoga thermarum str. DSM 5069, Pseudothermotoga thermarum strain DSM 5069, Thermotoga thermarum DSM 5069, Thermotoga thermarum LA3
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