Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEH52008.1COGs: COG1820 N-acetylglucosamine-6-phosphate deacetylase; InterPro IPR006680:IPR003764; KEGG: tle:Tlet_1990 N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase; PRIAM: N-acetylglucosamine-6-phosphate deacetylase; SPTR: N-acetylglucosamine-6-phosphate deacetylase; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; PFAM: Amidohydrolase family; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase. (374 aa)    
Predicted Functional Partners:
AEH51647.1
COGs: COG0363 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase; InterPro IPR006148:IPR018321; KEGG: phe:Phep_0774 glucosamine-6-phosphate deaminase; PFAM: glucosamine/galactosamine-6-phosphate isomerase; SPTR: Glucosamine-6-phosphate isomerase NAGB; PFAM: Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase; TIGRFAM: glucosamine-6-phosphate isomerase.
 0.998
murQ
Glucokinase regulatory-like protein; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate.
  
 0.979
AEH50424.1
N-acylglucosamine-6-phosphate 2-epimerase; COGs: COG3010 Putative N-acetylmannosamine-6-phosphate epimerase; InterPro IPR007260; KEGG: tle:Tlet_0111 N-acylglucosamine-6-phosphate 2-epimerase; PFAM: N-acetylmannosamine-6-phosphate epimerase; PRIAM: N-acylglucosamine-6-phosphate 2-epimerase; SPTR: N-acylglucosamine-6-phosphate 2-epimerase; PFAM: Putative N-acetylmannosamine-6-phosphate epimerase.
 
  
 0.951
glmS
Glutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
    
 0.913
AEH51433.1
Glutamine--fructose-6-phosphate transaminase (isomerizing); COGs: COG0449 Glucosamine 6-phosphate synthetase contains amidotransferase and phosphosugar isomerase domains; InterPro IPR001347; KEGG: dth:DICTH_1510 glucosamine--fructose-6-phosphate aminotransferase (isomerizing); PFAM: sugar isomerase (SIS); PRIAM: Glutamine--fructose-6-phosphate transaminase (isomerizing); SPTR: Putative uncharacterized protein; PFAM: SIS domain.
    
 0.913
AEH51512.1
Sugar isomerase (SIS); COGs: COG0449 Glucosamine 6-phosphate synthetase contains amidotransferase and phosphosugar isomerase domains; InterPro IPR017932:IPR000583:IPR001347; KEGG: tle:Tlet_1486 glutamine amidotransferase class-II; PFAM: sugar isomerase (SIS); glutamine amidotransferase class-II; SPTR: Glutamine amidotransferase class-II; PFAM: SIS domain; Glutamine amidotransferases class-II; TIGRFAM: glucosamine--fructose-6-phosphate aminotransferase (isomerizing).
    
 0.913
AEH50460.1
Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
     
 0.909
smc
Chromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family.
       0.716
AEH52010.1
NUDIX hydrolase; InterPro IPR020476:IPR020084:IPR000086; KEGG: tle:Tlet_1992 NUDIX hydrolase; PFAM: NUDIX hydrolase; SPTR: NUDIX hydrolase; PFAM: NUDIX domain; TIGRFAM: nudix-type nucleoside diphosphatase, YffH/AdpP family; Belongs to the Nudix hydrolase family.
  
    0.692
AEH52011.1
KEGG: tle:Tlet_1993 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.690
Your Current Organism:
Pseudothermotoga thermarum
NCBI taxonomy Id: 688269
Other names: P. thermarum DSM 5069, Pseudothermotoga thermarum DSM 5069, Pseudothermotoga thermarum LA3, Pseudothermotoga thermarum str. DSM 5069, Pseudothermotoga thermarum strain DSM 5069, Thermotoga thermarum DSM 5069, Thermotoga thermarum LA3
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