Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEH52025.1L-threonine 3-dehydrogenase; COGs: COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenase; InterPro IPR002328:IPR013154:IPR013149; KEGG: tle:Tlet_2010 alcohol dehydrogenase; PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; SPTR: Alcohol dehydrogenase GroES domain protein; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; TIGRFAM: L-threonine 3-dehydrogenase; 2-desacetyl-2-hydroxyethyl bacteriochlorophyllide A dehydrogenase. (344 aa)    
Predicted Functional Partners:
AEH52026.1
2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
 
 
 0.993
AEH51441.1
Pyridoxal-5'-phosphate-dependent protein beta subunit; COGs: COG1171 Threonine dehydratase; InterPro IPR000634:IPR001926; KEGG: tle:Tlet_1811 pyridoxal-5'-phosphate-dependent protein beta subunit; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Pyridoxal-5'-phosphate-dependent protein beta subunit; PFAM: Pyridoxal-phosphate dependent enzyme.
   
 
 0.911
AEH50487.1
L-threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.
   
 
 0.907
AEH52024.1
Extracellular solute-binding protein family 5; COGs: COG0747 ABC-type dipeptide transport system periplasmic component; InterPro IPR000914; KEGG: tle:Tlet_2008 extracellular solute-binding protein; PFAM: extracellular solute-binding protein family 5; SPTR: Extracellular solute-binding protein family 5; PFAM: Bacterial extracellular solute-binding proteins, family 5 Middle.
       0.489
AEH51809.1
Transaldolase; COGs: COG0176 Transaldolase; InterPro IPR001585; KEGG: tna:CTN_1544 fructose-6-phosphate aldolase; PFAM: Transaldolase; SPTR: Fructose-6-phosphate aldolase; PFAM: Transaldolase; TIGRFAM: fructose-6-phosphate aldolase, TalC/MipB family.
  
 
 0.424
AEH51806.1
COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590; KEGG: tna:CTN_1548 aldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; SPTR: Aldehyde dehydrogenase; PFAM: Aldehyde dehydrogenase family.
 
 
 0.411
Your Current Organism:
Pseudothermotoga thermarum
NCBI taxonomy Id: 688269
Other names: P. thermarum DSM 5069, Pseudothermotoga thermarum DSM 5069, Pseudothermotoga thermarum LA3, Pseudothermotoga thermarum str. DSM 5069, Pseudothermotoga thermarum strain DSM 5069, Thermotoga thermarum DSM 5069, Thermotoga thermarum LA3
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