Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEH52034.1Regulatory protein MarR; InterPro IPR000835; KEGG: pmo:Pmob_0959 MarR family transcriptional regulator; PFAM: regulatory protein MarR; SMART: regulatory protein MarR; SPTR: Transcriptional regulator, MarR family; PFAM: C-methyltransferase; MarR family. (212 aa)    
Predicted Functional Partners:
AEH52033.1
DegT/DnrJ/EryC1/StrS aminotransferase; COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR000653; KEGG: tle:Tlet_2019 DegT/DnrJ/EryC1/StrS aminotransferase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; SPTR: DegT/DnrJ/EryC1/StrS aminotransferase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase family; Belongs to the DegT/DnrJ/EryC1 family.
  
  
 0.974
AEH51668.1
Lipopolysaccharide biosynthesis protein; COGs: COG3206 Uncharacterized protein involved in exopolysaccharide biosynthesis; InterPro IPR003856; KEGG: taf:THA_872 chain length determinant protein; PFAM: lipopolysaccharide biosynthesis protein; SPTR: Chain length determinant protein; PFAM: Chain length determinant protein.
 
  
 0.920
AEH52032.1
Nucleotide sugar dehydrogenase; COGs: COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; InterPro IPR001732:IPR014026:IPR014027:IPR017476; KEGG: tle:Tlet_2018 UDP-glucose 6-dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; PRIAM: UDP-glucose 6-dehydrogenase; SPTR: UDP-glucose 6-dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; UDP-glucose/GDP-m [...]
  
  
 0.864
AEH50613.1
KEGG: tle:Tlet_1358 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Dienelactone hydrolase family.
 
     0.764
AEH51658.1
Polysaccharide biosynthesis protein; COGs: COG2244 Membrane protein involved in the export of O-antigen and teichoic acid; InterPro IPR002797; KEGG: fno:Fnod_0582 polysaccharide biosynthesis protein; PFAM: polysaccharide biosynthesis protein; SPTR: Polysaccharide biosynthesis protein; PFAM: Polysaccharide biosynthesis protein.
 
  
 0.761
AEH51669.1
Polysaccharide export protein; COGs: COG1596 Periplasmic protein involved in polysaccharide export; InterPro IPR003715:IPR019554; KEGG: taf:THA_873 polysaccharide export protein, putative; PFAM: polysaccharide export protein; Soluble ligand binding domain; SPTR: Polysaccharide export protein, putative; PFAM: Polysaccharide biosynthesis/export protein; SLBB domain.
 
  
 0.757
AEH50796.1
ExsB family protein; COGs: COG1606 ATP-utilizing protein of the PP-loop superfamily; KEGG: tle:Tlet_0612 ExsB family protein; SPTR: ExsB family protein; PFAM: NAD synthase.
  
     0.751
AEH51667.1
Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; COGs: COG2148 Sugar transferase involved in lipopolysaccharide synthesis; InterPro IPR017475:IPR003362; KEGG: tme:Tmel_1063 sugar transferase; PFAM: sugar transferase; PRIAM: Undecaprenyl-phosphate galactose phosphotransferase; SPTR: Sugar transferase; TIGRFAM: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; PFAM: Bacterial sugar transferase; TIGRFAM: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase.
  
  
 0.724
rnfG
Electron transport complex, RnfABCDGE type, G subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the RnfG family.
  
     0.722
AEH50702.1
COGs: COG3307 Lipid A core - O-antigen ligase; InterPro IPR007016; KEGG: tle:Tlet_0774 O-antigen polymerase; PFAM: O-antigen polymerase; SPTR: O-antigen polymerase; PFAM: O-Antigen ligase.
 
  
 0.687
Your Current Organism:
Pseudothermotoga thermarum
NCBI taxonomy Id: 688269
Other names: P. thermarum DSM 5069, Pseudothermotoga thermarum DSM 5069, Pseudothermotoga thermarum LA3, Pseudothermotoga thermarum str. DSM 5069, Pseudothermotoga thermarum strain DSM 5069, Thermotoga thermarum DSM 5069, Thermotoga thermarum LA3
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