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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH52036.1KEGG: tle:Tlet_2028 hypothetical protein; SPTR: Putative uncharacterized protein. (192 aa)    
Predicted Functional Partners:
cobB
Silent information regulator protein Sir2; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.
       0.827
rbsK-2
PfkB domain protein; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
       0.742
AEH52039.1
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.
       0.719
AEH52035.1
COGs: COG2164 conserved hypothetical protein; InterPro IPR007256; KEGG: tle:Tlet_2027 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Domain of unknown function (DUF369).
       0.653
AEH52032.1
Nucleotide sugar dehydrogenase; COGs: COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; InterPro IPR001732:IPR014026:IPR014027:IPR017476; KEGG: tle:Tlet_2018 UDP-glucose 6-dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; PRIAM: UDP-glucose 6-dehydrogenase; SPTR: UDP-glucose 6-dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; UDP-glucose/GDP-m [...]
       0.442
AEH52033.1
DegT/DnrJ/EryC1/StrS aminotransferase; COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR000653; KEGG: tle:Tlet_2019 DegT/DnrJ/EryC1/StrS aminotransferase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; SPTR: DegT/DnrJ/EryC1/StrS aminotransferase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase family; Belongs to the DegT/DnrJ/EryC1 family.
       0.442
AEH52034.1
Regulatory protein MarR; InterPro IPR000835; KEGG: pmo:Pmob_0959 MarR family transcriptional regulator; PFAM: regulatory protein MarR; SMART: regulatory protein MarR; SPTR: Transcriptional regulator, MarR family; PFAM: C-methyltransferase; MarR family.
       0.442
Your Current Organism:
Pseudothermotoga thermarum
NCBI taxonomy Id: 688269
Other names: P. thermarum DSM 5069, Pseudothermotoga thermarum DSM 5069, Pseudothermotoga thermarum LA3, Pseudothermotoga thermarum str. DSM 5069, Pseudothermotoga thermarum strain DSM 5069, Thermotoga thermarum DSM 5069, Thermotoga thermarum LA3
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