Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
AEH52050.1Inositol monophosphatase; COGs: COG0483 fructose-1 6-bisphosphatase of inositol monophosphatase family; InterPro IPR000760:IPR020583; KEGG: tle:Tlet_2048 inositol-phosphate phosphatase; PFAM: inositol monophosphatase; SPTR: Inositol-phosphate phosphatase; PFAM: Inositol monophosphatase family. (255 aa)    
Predicted Functional Partners:
AEH51898.1
Inositol monophosphatase; COGs: COG0483 fructose-1 6-bisphosphatase of inositol monophosphatase family; InterPro IPR000760:IPR020583; KEGG: tle:Tlet_1739 inositol-phosphate phosphatase; PFAM: inositol monophosphatase; SPTR: Inositol-phosphate phosphatase; PFAM: Inositol monophosphatase family.
  
  
 
0.915
AEH51166.1
Inositol 2-dehydrogenase; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR004104; KEGG: gka:GK1899 oxidoreductase; PFAM: oxidoreductase domain protein; Oxidoreductase domain; PRIAM: Inositol 2-dehydrogenase; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; Oxidoreductase family, C-terminal alpha/beta domain.
  
 
 0.908
AEH52048.1
COGs: COG1428 Deoxynucleoside kinase; InterPro IPR002624; KEGG: tle:Tlet_2046 deoxynucleoside kinase; PFAM: deoxynucleoside kinase; SPTR: Deoxynucleoside kinase; PFAM: Deoxynucleoside kinase.
       0.783
AEH52049.1
COGs: COG1428 Deoxynucleoside kinase; InterPro IPR002624; KEGG: tle:Tlet_2047 deoxynucleoside kinase; PFAM: deoxynucleoside kinase; SPTR: Deoxynucleoside kinase; PFAM: Deoxynucleoside kinase.
       0.783
uvrB
Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
       0.783
AEH52052.1
COGs: COG2930 conserved hypothetical protein; KEGG: tle:Tlet_2057 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Family of unknown function (DUF500).
  
    0.775
rimO
SSU ribosomal protein S12P methylthiotransferase; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily.
  
    0.745
AEH52044.1
CDP-diacylglycerol/glycerol-3-phosphate 3-phosphatidyltransferase; COGs: COG0558 Phosphatidylglycerophosphate synthase; InterPro IPR004570:IPR000462; KEGG: tle:Tlet_2042 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; SPTR: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol/glycerol-3-phosphate 3-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltr [...]
  
  
 0.744
nusA
NusA antitermination factor; Participates in both transcription termination and antitermination.
   
   0.735
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
   0.713
Your Current Organism:
Pseudothermotoga thermarum
NCBI taxonomy Id: 688269
Other names: P. thermarum DSM 5069, Pseudothermotoga thermarum DSM 5069, Pseudothermotoga thermarum LA3, Pseudothermotoga thermarum str. DSM 5069, Pseudothermotoga thermarum strain DSM 5069, Thermotoga thermarum DSM 5069, Thermotoga thermarum LA3
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