node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SKC39081.1 | SKC81355.1 | SAMN05660236_0086 | SAMN05660236_3934 | Uracil phosphoribosyltransferase. | Ribose 5-phosphate isomerase B. | 0.909 |
SKC39081.1 | glyA | SAMN05660236_0086 | SAMN05660236_3132 | Uracil phosphoribosyltransferase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.892 |
SKC57610.1 | SKC77080.1 | SAMN05660236_1716 | SAMN05660236_3507 | Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component. | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.746 |
SKC57610.1 | SKC81355.1 | SAMN05660236_1716 | SAMN05660236_3934 | Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component. | Ribose 5-phosphate isomerase B. | 0.677 |
SKC57610.1 | SKC82196.1 | SAMN05660236_1716 | SAMN05660236_4111 | Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component. | Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | 0.602 |
SKC57610.1 | pgl | SAMN05660236_1716 | SAMN05660236_3931 | Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component. | 6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. | 0.448 |
SKC77080.1 | SKC57610.1 | SAMN05660236_3507 | SAMN05660236_1716 | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component. | 0.746 |
SKC77080.1 | SKC81351.1 | SAMN05660236_3507 | SAMN05660236_3933 | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | 6-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. | 0.499 |
SKC77080.1 | SKC81355.1 | SAMN05660236_3507 | SAMN05660236_3934 | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | Ribose 5-phosphate isomerase B. | 0.732 |
SKC77080.1 | SKC82196.1 | SAMN05660236_3507 | SAMN05660236_4111 | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | 0.866 |
SKC77080.1 | gcvP | SAMN05660236_3507 | SAMN05660236_0099 | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | Glycine dehydrogenase (decarboxylating) alpha subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.475 |
SKC77080.1 | glyA | SAMN05660236_3507 | SAMN05660236_3132 | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.438 |
SKC81351.1 | SKC77080.1 | SAMN05660236_3933 | SAMN05660236_3507 | 6-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.499 |
SKC81351.1 | SKC81355.1 | SAMN05660236_3933 | SAMN05660236_3934 | 6-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. | Ribose 5-phosphate isomerase B. | 0.788 |
SKC81351.1 | SKC82196.1 | SAMN05660236_3933 | SAMN05660236_4111 | 6-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. | Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | 0.891 |
SKC81351.1 | glyA | SAMN05660236_3933 | SAMN05660236_3132 | 6-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.410 |
SKC81351.1 | pgl | SAMN05660236_3933 | SAMN05660236_3931 | 6-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. | 6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. | 0.983 |
SKC81355.1 | SKC39081.1 | SAMN05660236_3934 | SAMN05660236_0086 | Ribose 5-phosphate isomerase B. | Uracil phosphoribosyltransferase. | 0.909 |
SKC81355.1 | SKC57610.1 | SAMN05660236_3934 | SAMN05660236_1716 | Ribose 5-phosphate isomerase B. | Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component. | 0.677 |
SKC81355.1 | SKC77080.1 | SAMN05660236_3934 | SAMN05660236_3507 | Ribose 5-phosphate isomerase B. | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.732 |