SKC86002.1 protein (Ohtaekwangia koreensis) - STRING interaction network

Nodes:

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second shell of interactors

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Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

SKC86002.1

Uncharacterized iron-regulated membrane protein. (399 aa)

Predicted Functional Partners:

SKC86005.1

0.917

SKC86590.1

0.727

SKC86874.1

0.706

SKC61001.1

0.698

SKC76505.1

0.693

SKC83116.1

0.672

SKC81594.1

0.623

SKC87325.1

0.552

SKC85999.1

0.468

SKC86007.1

0.418

Your Current Organism:

Ohtaekwangia koreensis

NCBI taxonomy Id: 688867
Other names: Bacteroidetes bacterium 3B-2, CCUG 58939, DSM 25262, KCTC 23018, O. koreensis, Ohtaekwangia koreensis Yoon et al. 2011, strain 3B-2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SKC61001.1	SKC86002.1	SAMN05660236_2006	SAMN05660236_5024	Iron complex outermembrane recepter protein.	Uncharacterized iron-regulated membrane protein.	0.698
SKC76505.1	SKC86002.1	SAMN05660236_3407	SAMN05660236_5024	Iron complex outermembrane recepter protein; Manually curated.	Uncharacterized iron-regulated membrane protein.	0.693
SKC81594.1	SKC86002.1	SAMN05660236_3981	SAMN05660236_5024	Iron complex outermembrane recepter protein.	Uncharacterized iron-regulated membrane protein.	0.623
SKC83116.1	SKC86002.1	SAMN05660236_4369	SAMN05660236_5024	Iron complex outermembrane recepter protein.	Uncharacterized iron-regulated membrane protein.	0.672
SKC85999.1	SKC86002.1	SAMN05660236_5023	SAMN05660236_5024	Helix-turn-helix domain-containing protein.	Uncharacterized iron-regulated membrane protein.	0.468
SKC85999.1	SKC86005.1	SAMN05660236_5023	SAMN05660236_5025	Helix-turn-helix domain-containing protein.	Iron complex outermembrane recepter protein.	0.465
SKC86002.1	SKC61001.1	SAMN05660236_5024	SAMN05660236_2006	Uncharacterized iron-regulated membrane protein.	Iron complex outermembrane recepter protein.	0.698
SKC86002.1	SKC76505.1	SAMN05660236_5024	SAMN05660236_3407	Uncharacterized iron-regulated membrane protein.	Iron complex outermembrane recepter protein; Manually curated.	0.693
SKC86002.1	SKC81594.1	SAMN05660236_5024	SAMN05660236_3981	Uncharacterized iron-regulated membrane protein.	Iron complex outermembrane recepter protein.	0.623
SKC86002.1	SKC83116.1	SAMN05660236_5024	SAMN05660236_4369	Uncharacterized iron-regulated membrane protein.	Iron complex outermembrane recepter protein.	0.672
SKC86002.1	SKC85999.1	SAMN05660236_5024	SAMN05660236_5023	Uncharacterized iron-regulated membrane protein.	Helix-turn-helix domain-containing protein.	0.468
SKC86002.1	SKC86005.1	SAMN05660236_5024	SAMN05660236_5025	Uncharacterized iron-regulated membrane protein.	Iron complex outermembrane recepter protein.	0.917
SKC86002.1	SKC86007.1	SAMN05660236_5024	SAMN05660236_5026	Uncharacterized iron-regulated membrane protein.	Hypothetical protein.	0.418
SKC86002.1	SKC86590.1	SAMN05660236_5024	SAMN05660236_5187	Uncharacterized iron-regulated membrane protein.	Sulfite reductase (ferredoxin); Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.	0.727
SKC86002.1	SKC86874.1	SAMN05660236_5024	SAMN05660236_5277	Uncharacterized iron-regulated membrane protein.	Iron complex outermembrane recepter protein.	0.706
SKC86002.1	SKC87325.1	SAMN05660236_5024	SAMN05660236_5388	Uncharacterized iron-regulated membrane protein.	Ferredoxin-nitrate reductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.	0.552
SKC86005.1	SKC85999.1	SAMN05660236_5025	SAMN05660236_5023	Iron complex outermembrane recepter protein.	Helix-turn-helix domain-containing protein.	0.465
SKC86005.1	SKC86002.1	SAMN05660236_5025	SAMN05660236_5024	Iron complex outermembrane recepter protein.	Uncharacterized iron-regulated membrane protein.	0.917
SKC86005.1	SKC86007.1	SAMN05660236_5025	SAMN05660236_5026	Iron complex outermembrane recepter protein.	Hypothetical protein.	0.421
SKC86007.1	SKC86002.1	SAMN05660236_5026	SAMN05660236_5024	Hypothetical protein.	Uncharacterized iron-regulated membrane protein.	0.418

page 1 of 2

Network Stats

number of nodes:

11

number of edges:

55

average node degree:

10

avg. local clustering coefficient:

1

expected number of edges:

20

PPI enrichment p-value:

1.33e-10

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006914

Autophagy

10 of 63

2.15

6.81

1.02e-17

GO:0034727

Piecemeal microautophagy of the nucleus

3 of 7

2.58

2.42

3.14e-05

GO:0016236

Macroautophagy

4 of 34

2.02

2.32

1.67e-05

GO:0000045

Autophagosome assembly

3 of 19

2.15

1.83

0.00028

GO:0015031

Protein transport

8 of 355

1.3

1.75

4.19e-07

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0019776

Atg8 ligase activity

2 of 2

2.95

1.09

0.0106

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0000407

Phagophore assembly site

8 of 30

2.38

6.76

3.02e-15

GO:0034045

Phagophore assembly site membrane

6 of 17

2.5

5.43

1.51e-11

GO:0061908

Phagophore

2 of 2

2.95

1.5

0.0019

GO:0000421

Autophagosome membrane

2 of 2

2.95

1.5

0.0019

GO:0005774

Vacuolar membrane

3 of 127

1.33

0.64

0.0405

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:3886

Autophagy - other, and Autophagosome

9 of 28

2.46

8.08

4.71e-18

CL:3889

Autophagy - other

7 of 18

2.54

6.66

3.67e-14

CL:3911

Isopeptide bond, and Phagophore

5 of 5

2.95

5.58

4.16e-11

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map04136

Autophagy - other

7 of 24

2.42

6.29

7.37e-14

map04138

Autophagy - yeast

8 of 97

1.87

4.32

1.56e-12

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-9612973

Autophagy

9 of 58

2.14

6.2

8.97e-16

MAP-1632852

Macroautophagy

9 of 58

2.14

6.2

8.97e-16

MAP-8934903

Receptor Mediated Mitophagy

4 of 10

2.55

3.47

2.58e-07

MAP-5205647

Mitophagy

4 of 15

2.38

3.15

7.48e-07

MAP-9663891

Selective autophagy

4 of 24

2.17

2.74

3.15e-06

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0034045

Phagophore assembly site membrane

6 of 24

2.35

4.86

1.03e-10

GOCC:0000407

Phagophore assembly site

7 of 46

2.13

4.7

2.69e-11

GOCC:0016020

Membrane

8 of 1337

0.73

0.54

0.0043

GOCC:0005737

Cytoplasm

10 of 2932

0.48

0.35

0.0107

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0072

Autophagy

5 of 11

2.61

4.78

6.23e-10

KW-1017

Isopeptide bond

2 of 2

2.95

1.71

0.00081

KW-0833

Ubl conjugation pathway

3 of 38

1.85

1.5

0.00086

KW-0653

Protein transport

3 of 55

1.69

1.28

0.0019

KW-0813

Transport

4 of 251

1.15

0.82

0.0060

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF04110

Ubiquitin-like autophagy protein Apg12

2 of 2

2.95

1.21

0.0065

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